Competition and intrinsic displacement effects in overloaded weak affinity chromatography
Hubble, J., 2001. Competition and intrinsic displacement effects in overloaded weak affinity chromatography. Separation Science and Technology, 36 (4), pp. 541-554.
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A simple model is presented that describes the competitive adsorption of two components in a weak affinity adsorption system. Unlike previous models, the approach used here allows description of nonlinear isotherms operated under overloaded conditions. The results obtained suggest that, unlike std. elution protocols, significant concn. effects can be achieved in zonal operation as a result of intrinsic displacement effects, where a more strongly bound contaminant displaces a weakly bound product. [on SciFinder (R)]
|Uncontrolled Keywords||competition and intrinsic displacement effects in overloaded weak affinity chromatog.),adsorption (competitive,affinity chromatography (weak,preparative chromatography,adsorption isotherm overloaded weak affinity chromatog,simulation and modeling (competition and intrinsic displacement effects in overloaded weak affinity chromatog.)|
|Departments||Faculty of Engineering & Design > Chemical Engineering|
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