Regulating the motor for GLUT4 vesicle traffic

Reference:

Holman, G. D. and Sakamoto, K., 2008. Regulating the motor for GLUT4 vesicle traffic. Cell Metabolism, 8 (5), pp. 344-346.

Related documents:

Official URL:

http://dx.doi.org/10.1016/j.cmet.2008.10.006

Abstract

Insulin-triggered trafficking of GLUT4 glucose transporter-loaded vesicles and their fusion with the plasma membrane are mechanical processes involving multiprotein complexes that coordinate and facilitate vesicle movement. Now, Yip et al. (2008) link myosin-1 c to insulin signaling by demonstrating direct CaMKII-driven phosphorylation of this critical motor protein.

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