An atomic force microscope nanoscalpel for nanolithography and biological applications
Beard, J. D., Burbridge, D. J., Moskalenko, A. V., Dudko, O., Yarova, P. L., Smirnov, S. V. and Gordeev, S. N., 2009. An atomic force microscope nanoscalpel for nanolithography and biological applications. Nanotechnology, 20 (44), 445302.
Related documents:This repository does not currently have the full-text of this item.
You may be able to access a copy if URLs are provided below. (Contact Author)
We present the fabrication of specialized nanotools, termed nanoscalpels, and their application for nanolithography and nanomechanical manipulation of biological objects. Fabricated nanoscalpels have the shape of a thin blade with the controlled thickness of 20-30 nm and width of 100-200 nm. They were fabricated using electron beam induced deposition at the apex of atomic force microscope probes and are hard enough for a single cut to penetrate a similar to 45 nm thick gold layer; and thus can be used for making narrow electrode gaps required for fabrication of nanoelectronic devices. As an atomic force microscope-based technique the nanoscalpel provides simultaneous control of the applied cutting force and the depth of the cut. Using mammalian cells as an example, we demonstrated their ability to make narrow incisions and measurements of local elastic and inelastic characteristics of a cell, making nanoscalpels also useful as a nanosurgical tool in cell biology. Therefore, we believe that the nanoscalpel could serve as an important tool for nanofabrication and nanosurgery on biological objects.
|Creators||Beard, J. D., Burbridge, D. J., Moskalenko, A. V., Dudko, O., Yarova, P. L., Smirnov, S. V. and Gordeev, S. N.|
|Departments||Faculty of Science > Pharmacy & Pharmacology|
Faculty of Science > Physics
Actions (login required)