Research

Photorhabdus and a Host of Hosts


Reference:

Waterfield, N. R., Ciche, T. and Clarke, D., 2009. Photorhabdus and a Host of Hosts. Annual Review of Microbiology, 63, pp. 557-574.

Related documents:

This repository does not currently have the full-text of this item.
You may be able to access a copy if URLs are provided below. (Contact Author)

Official URL:

http://dx.doi.org/10.1146/annurev.micro.091208.073507

Abstract

Photorhabdus is a member of the family Enterobacteriaceae that lives in a mutualistic association with a Heterorhabditis nematode worm. The nematode worm burrows into insect prey and regurgitates Photohabdus, which goes on to kill the insect. The nematode feeds off the growing bacteria until the insect tissues are exhausted, whereupon they reassociate and leave the cadaver in search of new prey. This highly efficient partnership has been used for many years as a biological crop protection agent. The dual nature of Photorhabdus as a pathogen and mutualist makes it a superb model for understanding these apparently exclusive activities. Furthermore, recently identified clinical isolates of Photorhabdus helping us to understand how human pathogens can emerge from the enormous reservoir of invertebrate pathogens in the environment. As Photorhabdus has never been found outside a host animal, its niche represents an entirely biotic landscape. In this review we discuss what molecular adaptations allow this bacterium to complete this fascinating and complex life cycle.

Details

Item Type Articles
CreatorsWaterfield, N. R., Ciche, T. and Clarke, D.
DOI10.1146/annurev.micro.091208.073507
DepartmentsFaculty of Science > Biology & Biochemistry
RefereedYes
StatusPublished
ID Code16594

Export

Actions (login required)

View Item