Research

Coupling of Heck and hydrogenation reactions in a continuous compact reactor


Reference:

Fan, X. L., Manchon, M. G., Wilson, K., Tennison, S., Kozynchenko, A., Lapkin, A. A. and Plucinski, P. K., 2009. Coupling of Heck and hydrogenation reactions in a continuous compact reactor. Journal of Catalysis, 267 (2), pp. 114-120.

Related documents:

This repository does not currently have the full-text of this item.
You may be able to access a copy if URLs are provided below. (Contact Author)

Official URL:

http://dx.doi.org/10.1016/j.jcat.2009.07.019

Abstract

A continuous multi-step synthesis of 1,2-diphenylethane was performed sequentially in a structured compact reactor. This process involved a Heck C-C coupling reaction followed by the addition of hydrogen to perform reduction of the intermediate obtained in the first step. Both of the reactions were catalysed by microspherical carbon-supported Pd catalysts. Due to the integration of the micro-heat exchanger, the static mixer and the mesoscale packed-bed reaction channel, the compact reactor was proven to be an intensified tool for promoting the reactions. in comparison with the batch reactor, this flow process in the compact reactor was more efficient as: (i) the reaction time was significantly reduced (ca. 7 min versus several hours), (ii) no additional ligands were used and (iii) the reaction was run at lower operational pressure and temperature. Pd leached in the Heck reaction step was shown to be effectively recovered in the following hydrogenation reaction section and the catalytic activity of the system can be mostly retained by reverse flow operation. (C) 2009 Elsevier Inc. All rights reserved.

Details

Item Type Articles
CreatorsFan, X. L., Manchon, M. G., Wilson, K., Tennison, S., Kozynchenko, A., Lapkin, A. A. and Plucinski, P. K.
DOI10.1016/j.jcat.2009.07.019
DepartmentsFaculty of Engineering & Design > Chemical Engineering
RefereedYes
StatusPublished
ID Code16806

Export

Actions (login required)

View Item