Synthesis of furans, pyrroles and pyridazines by a ruthenium-catalysed isomerisation of alkynediols and in situ cyclisation
Reference:
Pridmore, S. J., Slatford, P. A., Taylor, J. E., Whittlesey, M. K. and Williams, J. M. J., 2009. Synthesis of furans, pyrroles and pyridazines by a ruthenium-catalysed isomerisation of alkynediols and in situ cyclisation. Tetrahedron, 65 (44), pp. 8981-8986.
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Official URL:
http://dx.doi.org/10.1016/j.tet.2009.06.108
Abstract
Alkyne-1,4-diols are readily available substrates which are isomerised to 1,4-diketones using Ru(PPh3)(3)(CO)H-2/xantphos as a catalyst. In situ cyclisation into furans, pyrroles and pyridazines has been achieved under suitable conditions. (C) 2009 Elsevier Ltd. All rights reserved.
Details
| Item Type | Articles |
| Creators | Pridmore, S. J., Slatford, P. A., Taylor, J. E., Whittlesey, M. K. and Williams, J. M. J. |
| DOI | 10.1016/j.tet.2009.06.108 |
| Departments | Faculty of Science > Chemistry |
| Refereed | Yes |
| Status | Published |
| ID Code | 17083 |
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