Fabrication of BioFET Linear Array for Detection of Protein Interactions
Reference:
Wang, L., Estrela, P., Huq, E., Li, P., Thomas, S., Ko Ferrigno, P., Paul, D., Adkin, P. and Migliorato, P., 2010. Fabrication of BioFET Linear Array for Detection of Protein Interactions. Microelectronic Engineering, 87 (5-8), pp. 753-755.
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Official URL:
http://dx.doi.org/10.1016/j.mee.2009.11.148
Abstract
An extended-gate MOSFETs (metal–oxide-semiconductor field-effect transistors) based biosensing linear array has been fabricated for label-free protein interaction detection. The device was realized using a combination of very low leakage current MOSFET transistors and an external gate where the chemical reaction would take place. Peptide aptamers that recognize cyclin-dependent kinase (CDK), a protein cancer marker, were used as a biological test system. The test results showed a high sensitive in the detection of CDK.
Details
| Item Type | Articles |
| Creators | Wang, L., Estrela, P., Huq, E., Li, P., Thomas, S., Ko Ferrigno, P., Paul, D., Adkin, P. and Migliorato, P. |
| DOI | 10.1016/j.mee.2009.11.148 |
| Departments | Faculty of Engineering & Design > Electronic & Electrical Engineering |
| Research Centres | Centre for Advanced Sensor Technologies (CAST) |
| Refereed | Yes |
| Status | Published |
| ID Code | 18027 |
| Additional Information | The 35th International Conference on Micro- and Nano-Engineering (MNE), The 35th International Conference on Micro- and Nano-Engineering (MNE) |
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- Fabrication of BioFET Linear Array for Detection of Protein Interactions. (deposited 01 Mar 2010 09:05)[Currently Displayed]
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