Research

Endometriosis and its coexistence with irritable bowel syndrome and pelvic inflammatory disease: findings from a national case-control study - Part 2


Reference:

Seaman, H. E., Ballard, K. D., Wright, J. T. and de Vries, C. S., 2008. Endometriosis and its coexistence with irritable bowel syndrome and pelvic inflammatory disease: findings from a national case-control study - Part 2. BJOG : An International Journal Of Obstetrics & Gynaecology, 115 (11), pp. 1392-1396.

Related documents:

This repository does not currently have the full-text of this item.
You may be able to access a copy if URLs are provided below. (Contact Author)

Official URL:

http://dx.doi.org/10.1111/j.1471-0528.2008.01879.x

Abstract

Objective: To investigate whether the increased chances of having a diagnosis of irritable bowel syndrome (IBS) and pelvic inflammatory disease (PID) in women with endometriosis is due to misdiagnosis or co-morbidity. Design: A case-control study of women aged 15-55 years with endometriosis and matched controls. Setting Data: from the UK's General Practice Research Database for the years 1992-2001. Sample: A total of 5540 women aged 15-55 years, diagnosed with endometriosis, each matched to four controls without endometriosis. The index date was defined as the date of diagnosis. Methods: Data were analysed to determine whether women with endometriosis were more likely to receive a diagnosis of PIDor IBS than women without endometriosis. Odds ratios were calculated for endometriosis associated with IBS and PID before and after the index date. Main outcome measures: Diagnosis of IBS or PID before and after the index date. Results: Compared with the controls, women with endometriosis were 3.5 times more likely to have received a diagnosis of IBS (OR 3.5 [95% CI: 3.1-3.9]). Even after women had been diagnosed with endometriosis, they were still two and a half times more likely to receive a new diagnosis of IBS when compared with the controls (OR 2.5 [95% CI: 2.2-2.8]). Similarly, women with endometriosis were more likely than those without endometriosis to have been treated for PID both before (OR 5.9 [95% CI: 5.1-6.9]) and after (OR 3.8 [95% CI: 3.1-4.6]) being diagnosed with endometriosis. Conclusions: Women with endometriosis are more likely to be diagnosed with IBS and PID than controls, even after a definitive diagnosis of endometriosis has been reached.

Details

Item Type Articles
CreatorsSeaman, H. E., Ballard, K. D., Wright, J. T. and de Vries, C. S.
DOI10.1111/j.1471-0528.2008.01879.x
Uncontrolled Keywordsmisdiagnosis, co-morbidity, endometriosis, irritable bowel syndrome, diagnostic error, pelvic inflammatory disease
DepartmentsFaculty of Science > Pharmacy & Pharmacology
RefereedYes
StatusPublished
ID Code19841

Export

Actions (login required)

View Item