Borrowing hydrogen in water and ionic liquids: iridium-catalyzed alkylation of amines with alcohols
Saidi, O., Blacker, A. J., Lamb, G. W., Marsden, S. P., Taylor, J. E. and Williams, J. M. J., 2010. Borrowing hydrogen in water and ionic liquids: iridium-catalyzed alkylation of amines with alcohols. Organic Process Research & Development, 14 (4), pp. 1046-1049.
Related documents:This repository does not currently have the full-text of this item.
You may be able to access a copy if URLs are provided below. (Contact Author)
The use of [Cp*IrI2](2) as an efficient catalyst for the alkylation of amines by alcohols in either water or ionic liquid is described. Primary amines are converted into secondary amines, and secondary amines into tertiary amines in the absence of base, and the chemistry has been applied to the synthesis of the analgesic fentanyl. The conversion of primary amines into N-heterocycles by the reaction with diols is also described, along with the N-alkylation of sulfonamides.
|Creators||Saidi, O., Blacker, A. J., Lamb, G. W., Marsden, S. P., Taylor, J. E. and Williams, J. M. J.|
|Departments||Faculty of Science > Chemistry|
Faculty of Engineering & Design > Chemical Engineering
Actions (login required)