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Drosophila melanogaster embryonic haemocytes: masters of multitasking


Reference:

Wood, W. and Jacinto, A., 2007. Drosophila melanogaster embryonic haemocytes: masters of multitasking. Nature Reviews Molecular Cell Biology, 8 (7), pp. 542-551.

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Official URL:

http://dx.doi.org/10.1038/nrm2202

Abstract

Drosophila melanogaster haemocytes constitute the cellular arm of a robust innate immune system in flies. In the adult and larva, these cells operate as the first line of defence against invading microorganisms: they phagocytose pathogens and produce antimicrobial peptides. However, in the sterile environment of the embryo, these important immune functions are largely redundant. Instead, throughout development, embryonic haemocytes are occupied with other tasks: they undergo complex migrations and carry out several non-immune functions that are crucial for successful embryogenesis.

Details

Item Type Articles
CreatorsWood, W.and Jacinto, A.
DOI10.1038/nrm2202
DepartmentsFaculty of Science > Biology & Biochemistry
RefereedYes
StatusPublished
ID Code21032

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