Surfactant-free poly(lactide-co-glycolide) honeycomb films for tissue engineering: relating solvent, monomer ratio and humidity to scaffold structure
Reference:
Wu, X., Jones, M. D., Davidson, M. G., Chaudhuri, J. B. and Ellis, M. J., 2011. Surfactant-free poly(lactide-co-glycolide) honeycomb films for tissue engineering: relating solvent, monomer ratio and humidity to scaffold structure. Biotechnology Letters, 33 (2), pp. 423-430.
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Official URL:
http://dx.doi.org/10.1007/s10529-010-0438-y
Abstract
One-step surfactant-free, water-droplet templating has been developed as a fabrication method for a poly(lactide-co-glycolide) (PLGA) film that can be used as a model to investigate the relationship between solvent, monomer ratio, polymer concentration and humidity on its structure. The resulting material is a honeycomb-structured film. Formation of this structure was highly sensitive to solvent, monomer ratio, polymer concentration and humidity. Surfactant-free, water-droplet templating thus allows investigation of fabrication parameters and that PLGA monomer ratio selection is important for scaffold structure but not for MG63 cell attachment and proliferation.
Details
| Item Type | Articles |
| Creators | Wu, X., Jones, M. D., Davidson, M. G., Chaudhuri, J. B. and Ellis, M. J. |
| DOI | 10.1007/s10529-010-0438-y |
| Departments | Faculty of Engineering & Design > Chemical Engineering Faculty of Science > Chemistry |
| Research Centres | Centre for Regenerative Medicine |
| Publisher Statement | Wu_BILE_Honeycomb_2010_REVISED_2.pdf: The original publication is available at www.springerlink.com |
| Refereed | Yes |
| Status | Published |
| ID Code | 21397 |
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