Wu, X., Jones, M. D., Davidson, M. G., Chaudhuri, J. B. and Ellis, M. J., 2011. Surfactant-free poly(lactide-co-glycolide) honeycomb films for tissue engineering: relating solvent, monomer ratio and humidity to scaffold structure. Biotechnology Letters, 33 (2), pp. 423-430.
One-step surfactant-free, water-droplet templating has been developed as a fabrication method for a poly(lactide-co-glycolide) (PLGA) film that can be used as a model to investigate the relationship between solvent, monomer ratio, polymer concentration and humidity on its structure. The resulting material is a honeycomb-structured film. Formation of this structure was highly sensitive to solvent, monomer ratio, polymer concentration and humidity. Surfactant-free, water-droplet templating thus allows investigation of fabrication parameters and that PLGA monomer ratio selection is important for scaffold structure but not for MG63 cell attachment and proliferation.
|Item Type ||Articles|
|Creators||Wu, X., Jones, M. D., Davidson, M. G., Chaudhuri, J. B. and Ellis, M. J.|
|Departments||Faculty of Engineering & Design > Chemical Engineering|
Faculty of Science > Chemistry
|Research Centres||Centre for Regenerative Medicine|
|Publisher Statement||Wu_BILE_Honeycomb_2010_REVISED_2.pdf: The original publication is available at www.springerlink.com|
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