Rhodium-catalysed conjugate addition of arylboronic acids to enantiopure dehydroamino acid derivatives
Hargrave, J. D., Bish, G., Kociok-Kohn, G. and Frost, C. G., 2010. Rhodium-catalysed conjugate addition of arylboronic acids to enantiopure dehydroamino acid derivatives. Organic and Biomolecular Chemistry, 8 (22), pp. 5120-5125.
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The rhodium-catalysed conjugate addition of arylboronic acids to an enantiopure acceptor derived from (R)-S-methylcysteine proceeds under substrate control to provide a range of functionalised phenylalanine derivatives with excellent stereocontrol via a highly diastereoselective protonation.
|Creators||Hargrave, J. D., Bish, G., Kociok-Kohn, G. and Frost, C. G.|
|Departments||Faculty of Science > Chemistry|
Faculty of Science > Pharmacy & Pharmacology
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