Rhodium-catalysed conjugate addition of arylboronic acids to enantiopure dehydroamino acid derivatives
Reference:
Hargrave, J. D., Bish, G., Kociok-Kohn, G. and Frost, C. G., 2010. Rhodium-catalysed conjugate addition of arylboronic acids to enantiopure dehydroamino acid derivatives. Organic and Biomolecular Chemistry, 8 (22), pp. 5120-5125.
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Official URL:
http://dx.doi.org/10.1039/c0ob00158a
Abstract
The rhodium-catalysed conjugate addition of arylboronic acids to an enantiopure acceptor derived from (R)-S-methylcysteine proceeds under substrate control to provide a range of functionalised phenylalanine derivatives with excellent stereocontrol via a highly diastereoselective protonation.
Details
| Item Type | Articles |
| Creators | Hargrave, J. D., Bish, G., Kociok-Kohn, G. and Frost, C. G. |
| DOI | 10.1039/c0ob00158a |
| Departments | Faculty of Science > Chemistry Faculty of Science > Pharmacy & Pharmacology |
| Refereed | Yes |
| Status | Published |
| ID Code | 21609 |
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