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Rhodium-catalysed conjugate addition of arylboronic acids to enantiopure dehydroamino acid derivatives


Reference:

Hargrave, J. D., Bish, G., Kociok-Kohn, G. and Frost, C. G., 2010. Rhodium-catalysed conjugate addition of arylboronic acids to enantiopure dehydroamino acid derivatives. Organic and Biomolecular Chemistry, 8 (22), pp. 5120-5125.

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Official URL:

http://dx.doi.org/10.1039/c0ob00158a

Abstract

The rhodium-catalysed conjugate addition of arylboronic acids to an enantiopure acceptor derived from (R)-S-methylcysteine proceeds under substrate control to provide a range of functionalised phenylalanine derivatives with excellent stereocontrol via a highly diastereoselective protonation.

Details

Item Type Articles
CreatorsHargrave, J. D., Bish, G., Kociok-Kohn, G. and Frost, C. G.
DOI10.1039/c0ob00158a
DepartmentsFaculty of Science > Chemistry
Faculty of Science > Pharmacy & Pharmacology
RefereedYes
StatusPublished
ID Code21609

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