Research

Experience-dependent modification of mechanisms of long-term depression.


Reference:

Jo, J., Ball, S. M., Seok, H., Oh, S. B., Massey, P. V., Molnar, E., Bashir, Z. I. and Cho, K., 2006. Experience-dependent modification of mechanisms of long-term depression. Nature Neuroscience, 9, pp. 170-172.

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http://www.nature.com/neuro/journal/v9/n2/full/nn1637.html

Abstract

Mechanisms of long-term potentiation and depression (LTP and LTD) change considerably during development, but the importance of these changes and the factors that control them is not clear. We found that visual experience triggered a switch in mechanisms of LTD in rat perirhinal cortex, an area critical for visual recognition memory. Thus, changes in synaptic plasticity mechanisms were correlated with the changing physiological demands on the CNS.

Details

Item Type Articles
CreatorsJo, J., Ball, S. M., Seok, H., Oh, S. B., Massey, P. V., Molnar, E., Bashir, Z. I. and Cho, K.
DOI10.1038/nn1637
DepartmentsFaculty of Science > Pharmacy & Pharmacology
RefereedYes
StatusPublished
ID Code23422

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