AFM nanotools for surgery of biological Cells

Reference:

Beard, J. D., Gordeev, S. N. and Guy, R. H., 2011. AFM nanotools for surgery of biological Cells. Journal of Physics: Conference Series, 286 (1), 012003.

Related documents:

Official URL:

http://dx.doi.org/10.1088/1742-6596/286/1/012003

Related URLs:

• http://www.scopus.com/inward/record.url?scp=79955908509&partnerID=8YFLogxK

Abstract

Using a method of electron-beam induced deposition, we have been able to fabricate specialized AFM probes with application as "nanotools" for the manipulation of biological structures ("nanosurgery"). We describe several such tools, including a "nanoscalpel", " nanoneedles" for probing intracellular structures, and a "nanotome" which can separate surface layers from a biological structure. These applications are demonstrated by performing nanomanipulation on corneocyte cells from the outer layer of human skin.

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