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microRNAs and the immune response


Reference:

Lindsay, M. A., 2008. microRNAs and the immune response. Trends in Immunology, 29 (7), pp. 343-351.

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Official URL:

http://dx.doi.org/10.1016/j.it.2008.04.004

Abstract

Review microRNA (miRNA)-mediated RNA interference has been identified as a novel mechanism that regulates protein expression at the translational level. Recent publications have provided compelling evidence that a range of miRNAs are involved in the regulation of immunity, including the development and differentiation of B and T cells, proliferation of monocytes and neutrophils, antibody switching and the release of inflammatory mediators. In this review, we examine what is presently known of the function and mechanism of action of these miRNAs in the regulation of the innate and acquired immune response.

Details

Item Type Articles
CreatorsLindsay, M. A.
DOI10.1016/j.it.2008.04.004
DepartmentsFaculty of Science > Pharmacy & Pharmacology
RefereedYes
StatusPublished
ID Code24570

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