Design and synthesis of artificial ion channels

Reference:

Cross, G. G., Fyles, T. M., James, T. D. and Zojaji, M., 1993. Design and synthesis of artificial ion channels. Synlett, 1993 (07), pp. 449-460.

Related documents:

Official URL:

http://dx.doi.org/10.1055/s-1993-22489

Abstract

The synthesis of a series of functional artifical ion channels is described. Candidate structures are assembled from a modular construction set of subunits consisting of a core crown ether unit for structural organization, multiple macrocyclic tetraester wall units to span a bilayer membrane, and polar head units to impart amphiphilic character. The modular assembly approach allowed the efficient synthesis of a suite of compounds but the inherent properties of the construction set limited the range of synthetically accessible structures.

Export

Actions (login required)