Sat-Nav for T cells: Role of PI3K isoforms and lipid phosphatases in migration of T lymphocytes
Reference:
Ward, S. G., Westwick, J. and Harris, S., 2011. Sat-Nav for T cells: Role of PI3K isoforms and lipid phosphatases in migration of T lymphocytes. Immunology Letters, 138 (1), pp. 15-18.
Related documents:
This repository does not currently have the full-text of this item.You may be able to access a copy if URLs are provided below. (Contact Author)
Official URL:
http://dx.doi.org/10.1016/j.imlet.2011.02.007
Abstract
Phosphoinositide 3-kinase (PI3K)-dependent signaling has been placed at the heart of conserved biochemical mechanisms that facilitate cell migration of leukocytes in response to a range of chemoattractant stimuli. This review assesses the evidence for and against PI3K-dependent mechanisms of T lymphocyte migration and whether pharmacological targeting of PI3K isoforms is likely to offer potential benefit for T cell mediated pathologies.
Details
| Item Type | Articles |
| Creators | Ward, S. G., Westwick, J. and Harris, S. |
| DOI | 10.1016/j.imlet.2011.02.007 |
| Uncontrolled Keywords | migration, inhibitors, t lymphocytes, pi3k |
| Departments | Faculty of Science > Pharmacy & Pharmacology |
| Refereed | Yes |
| Status | Published |
| ID Code | 25095 |
Export
Actions (login required)
| View Item |
