Research

Behavioural and psychiatric symptoms in patients with neurodegenerative diseases


Reference:

Lomax, C. L., Brown, R. G., Chaudhuri, K. and Howard, R. J., 2005. Behavioural and psychiatric symptoms in patients with neurodegenerative diseases. Brain Impairment, 6 (3), pp. 181-190.

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Official URL:

http://dx.doi.org/10.1375/brim.2005.6.3.181

Abstract

Neuropsychiatric symptoms are common features in patients with neurodegenerative diseases, and have important clinical implications for both patients and caregivers. This study used the Neuropsychiatric Inventory (NPI) to measure symptomatology in 120 patients drawn from five disease groups: Parkinson's disease (PD), Alzheimer's disease (AD), dementia associated with Lewy bodies (DLB), multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). Ninety per cent of the patient group reported experiencing at least one symptom, with the most prevalent symptoms being depression and apathy. However, a differential pattern of symptomatology was reported across the disease groups, a finding which has diagnostic and treatment implications. Furthermore, this provides additional evidence that a broad cortical-subcortical distinction cannot be supported.

Details

Item Type Articles
CreatorsLomax, C. L., Brown, R. G., Chaudhuri, K. and Howard, R. J.
DOI10.1375/brim.2005.6.3.181
DepartmentsFaculty of Humanities & Social Sciences > Psychology
RefereedYes
StatusPublished
ID Code26215

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