Pathogenic mechanisms of disease in myositis: autoantigens as clues

Reference:

Betteridge, Z. E., Gunawardena, H. and McHugh, N. J., 2009. Pathogenic mechanisms of disease in myositis: autoantigens as clues. Current Opinion in Rheumatology, 21 (6), pp. 604-9.

Related documents:

Official URL:

http://dx.doi.org/10.1097/BOR.0b013e328331638a

Abstract

There are now a number of models indicating roles of autoantigens in disease pathogenesis. Our increased understanding of the autoantigenic properties of these targeted proteins will help to determine the mechanisms involved in the initiation and propagation of myositis. In turn, these findings may lead to therapeutic advances including the development of more targeted treatments.

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