Research

HLA-DPB1 associations differ between DRB1*03 positive anti-Jo-1 and anti-PM-Scl antibody positive idiopathic inflammatory myopathy


Reference:

Chinoy, H., Payne, D., Poulton, K. V., Fertig, N., Betteridge, Z., Gunawardena, H., Davidson, J. E., Oddis, C. V., McHugh, N. J., Wedderburn, L. R., Ollier, W. E. and Cooper, R. G., 2009. HLA-DPB1 associations differ between DRB1*03 positive anti-Jo-1 and anti-PM-Scl antibody positive idiopathic inflammatory myopathy. Rheumatology, 48 (10), pp. 1213-7.

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Official URL:

http://dx.doi.org/10.1093/rheumatology/kep248

Abstract

The HLA-DRB1*03/DPB1*0101 haplotype is a risk factor for anti-Jo-1 antibody-positive IIM. Thus, although DRB1*03 is strongly associated with possession of either anti-Jo-1 or anti-PM-Scl, differing antibody associations are observed at the HLA-DPB1 locus.

Details

Item Type Articles
CreatorsChinoy, H., Payne, D., Poulton, K. V., Fertig, N., Betteridge, Z., Gunawardena, H., Davidson, J. E., Oddis, C. V., McHugh, N. J., Wedderburn, L. R., Ollier, W. E. and Cooper, R. G.
DOI10.1093/rheumatology/kep248
DepartmentsFaculty of Science > Pharmacy & Pharmacology
Faculty of Humanities & Social Sciences > Health
RefereedYes
StatusPublished
ID Code27486

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