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Associations of erosive arthritis with anti-cyclic citrullinated peptide antibodies and MHC Class II alleles in systemic lupus erythematosus.


Reference:

Chan, M. T., Owen, P., Dunphy, J., Cox, B., Carmichael, C., Korendowych, E. and McHugh, N. J., 2008. Associations of erosive arthritis with anti-cyclic citrullinated peptide antibodies and MHC Class II alleles in systemic lupus erythematosus. Journal of Rheumatology, 35 (1), pp. 77-83.

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Official URL:

http://www.jrheum.org/content/35/1/77.abstract

Abstract

The frequency of EA in SLE is likely to be higher than previously reported. Anti-CCP+ patients with SLE are more likely to have EA. Anti-CCP may be a useful serological marker for EA for patients presenting with synovitis. Anti-citrulline antibodies may have a pathogenic role in the development of major erosions, resulting in clinical features that overlap SLE with RA (rhupus).

Details

Item Type Articles
CreatorsChan, M. T., Owen, P., Dunphy, J., Cox, B., Carmichael, C., Korendowych, E. and McHugh, N. J.
DepartmentsFaculty of Science > Pharmacy & Pharmacology
Faculty of Humanities & Social Sciences > Health
RefereedYes
StatusPublished
ID Code27490

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