Magnesium-catalyzed hydroboration of pyridines

Reference:

Arrowsmith, M., Hill, M. S., Hadlington, T., Kociok-Kohn, G. and Weetman, C., 2011. Magnesium-catalyzed hydroboration of pyridines. Organometallics, 30 (21), pp. 5556-5559.

Related documents:

Official URL:

http://dx.doi.org/10.1021/om2008138

Abstract

Reaction of catalytic quantities of a -diketiminato n-butylmagnesium complex with pinacol-borane in the presence of pyridine derivatives provides facile access to borylated dihydropyridines. The reaction is applicable to a wide range of monocyclic and fused-ring pyridine derivatives and catalytic turnover is proposed to occur through a well-defined sequence of Mg-H/pyridine dearomatization and Mg-N/B-H sigma bond metathesis steps.

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