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HLA class II haplotype and autoantibody associations in children with juvenile dermatomyositis and juvenile dermatomyositis-scleroderma overlap


Reference:

Wedderburn, L. R., McHugh, N. J., Chinoy, H., Cooper, R. G., Salway, F., Ollier, W. E. R., McCann, L. J., Varsani, H., Dunphy, J., North, J. and Davidson, J. E., 2007. HLA class II haplotype and autoantibody associations in children with juvenile dermatomyositis and juvenile dermatomyositis-scleroderma overlap. Rheumatology, 46 (12), pp. 1786-1791.

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Official URL:

http://dx.doi.org/10.1093/rheumatology/kem265

Abstract

We present clinical data, HLA genotyping and serological profiling on a large cohort of JDM patients and a carefully characterized subset of patients with JDM-SSc overlap. The results confirm known HLA associations and extend the knowledge by stratification of data in serological and clinical subgroups. In the future, a combination of serological and genetic typing may allow for better prediction of clinical course and disease subtype in JDM.

Details

Item Type Articles
CreatorsWedderburn, L. R., McHugh, N. J., Chinoy, H., Cooper, R. G., Salway, F., Ollier, W. E. R., McCann, L. J., Varsani, H., Dunphy, J., North, J. and Davidson, J. E.
DOI10.1093/rheumatology/kem265
DepartmentsFaculty of Science > Pharmacy & Pharmacology
Faculty of Humanities & Social Sciences > Health
RefereedYes
StatusPublished
ID Code27947

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