Identification of a novel autoantibody directed against small ubiquitin-like modifier activating enzyme in dermatomyositis

Reference:

Betteridge, Z., Gunawardena, H., North, J., Slinn, J. and McHugh, N. J., 2007. Identification of a novel autoantibody directed against small ubiquitin-like modifier activating enzyme in dermatomyositis. Arthritis & Rheumatism, 56 (9), pp. 3132-3137.

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Official URL:

http://dx.doi.org/10.1002/art.22862

Abstract

These findings reveal previously uncharacterized autoantibodies directed against a protein involved in posttranslational modification, the SUMO activating enzyme, in 2 patients with DM who had similar clinical features, including severe skin disease and interstitial pneumonia.

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