Grant, J., Jack, R. L. and Whitelam, S., 2011. Analyzing mechanisms and microscopic reversibility of self-assembly. Journal of Chemical Physics, 135 (21), 214505.
We use computer simulations to investigate self-assembly in a system of model chaperonin proteins, and in an Ising lattice gas. We discuss the mechanisms responsible for rapid and efficient assembly in these systems, and we use measurements of dynamical activity and assembly progress to compare their propensities for kinetic trapping. We use the analytic solution of a simple minimal model to illustrate the key features associated with such trapping, paying particular attention to the number of ways that particles can misbind. We discuss the relevance of our results for the design and control of self-assembly in general.
|Item Type ||Articles|
|Creators||Grant, J., Jack, R. L. and Whitelam, S.|
|Departments||Faculty of Science > Physics|
|Publisher Statement||Jack_JCP_2011_135_214505.pdf: Copyright (2011) American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Grant, J., Jack, R. L. and Whitelam, S., 2011. Analyzing mechanisms and microscopic reversibility of self-assembly. Journal of Chemical Physics, 135 (21) and may be found at http://dx.doi.org/10.1063/1.3662140|
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