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Templated dynamic synthesis of a [3]catenane


Reference:

Cougnon, F. B. L., Jenkins, N. A., Pantoș, G. D. and Sanders, J. K. M., 2012. Templated dynamic synthesis of a [3]catenane. Angewandte Chemie-International Edition, 51 (6), pp. 1443-1447.

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Official URL:

http://dx.doi.org/10.1002/anie.201106885

Abstract

The self-assembly of a water-soluble [3]catenane from a library composed of two linear building blocks, both terminated by cysteine components, is promoted either by a high salt concentration or by the presence of spermine. The spermine-templated synthesis of the [3]catenane shows that such structures can exhibit strong binding interactions with a biologically relevant target in water under near-physiological conditions.

Details

Item Type Articles
CreatorsCougnon, F. B. L., Jenkins, N. A., Pantoș, G. D. and Sanders, J. K. M.
DOI10.1002/anie.201106885
DepartmentsFaculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code28195

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