Templated dynamic synthesis of a catenane
Cougnon, F. B. L., Jenkins, N. A., Pantoș, G. D. and Sanders, J. K. M., 2012. Templated dynamic synthesis of a catenane. Angewandte Chemie-International Edition, 51 (6), pp. 1443-1447.
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The self-assembly of a water-soluble catenane from a library composed of two linear building blocks, both terminated by cysteine components, is promoted either by a high salt concentration or by the presence of spermine. The spermine-templated synthesis of the catenane shows that such structures can exhibit strong binding interactions with a biologically relevant target in water under near-physiological conditions.
|Creators||Cougnon, F. B. L., Jenkins, N. A., Pantoș, G. D. and Sanders, J. K. M.|
|Departments||Faculty of Science > Chemistry|
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