Direct amide formation from unactivated carboxylic acids and amines
Reference:
Allen, C. L., Chhatwal, A. R. and Williams, J. M. J., 2012. Direct amide formation from unactivated carboxylic acids and amines. Chemical Communications, 48 (5), pp. 666-668.
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Official URL:
http://dx.doi.org/10.1039/c1cc15210f
Abstract
The direct coupling of unactivated carboxylic acids with amines can be performed in toluene 110 degrees C in the absence of catalyst. The use of simple zirconium catalysts at 5 mol% loading gave amide formation in as little as 4 h.
Details
| Item Type | Articles |
| Creators | Allen, C. L., Chhatwal, A. R. and Williams, J. M. J. |
| DOI | 10.1039/c1cc15210f |
| Departments | Faculty of Science > Chemistry |
| Refereed | Yes |
| Status | Published |
| ID Code | 28202 |
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