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Direct amide formation from unactivated carboxylic acids and amines


Reference:

Allen, C. L., Chhatwal, A. R. and Williams, J. M. J., 2012. Direct amide formation from unactivated carboxylic acids and amines. Chemical Communications, 48 (5), pp. 666-668.

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Official URL:

http://dx.doi.org/10.1039/c1cc15210f

Abstract

The direct coupling of unactivated carboxylic acids with amines can be performed in toluene 110 degrees C in the absence of catalyst. The use of simple zirconium catalysts at 5 mol% loading gave amide formation in as little as 4 h.

Details

Item Type Articles
CreatorsAllen, C. L., Chhatwal, A. R. and Williams, J. M. J.
DOI10.1039/c1cc15210f
DepartmentsFaculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code28202

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