Research

Mechanistic studies into metal-catalyzed aldoxime to amide rearrangements


Reference:

Allen, C. L., Lawrence, R., Emmett, L. and Williams, J. M. J., 2011. Mechanistic studies into metal-catalyzed aldoxime to amide rearrangements. Advanced Synthesis & Catalysis, 353 (18), pp. 3262-3268.

Related documents:

This repository does not currently have the full-text of this item.
You may be able to access a copy if URLs are provided below. (Contact Author)

Official URL:

http://dx.doi.org/10.1002/adsc.201100650

Abstract

The metal-catalyzed rearrangement of aldoximes into primary amides is a completely atom economical synthetic method for the preparation of one of the most important functional groups in chemistry. There have been several reports of various metals successfully catalyzing this reaction, however, there are conflicting views as to the mechanism involved. Herein we report new experimental evidence to support the mechanism and whether this is universal to all catalysts reported or metal specific. We also describe our further studies into the mechanism of the nickel-catalyzed acylation of amines with aldoximes.

Details

Item Type Articles
CreatorsAllen, C. L., Lawrence, R., Emmett, L. and Williams, J. M. J.
DOI10.1002/adsc.201100650
DepartmentsFaculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code28427

Export

Actions (login required)

View Item