Therapeutics
Reference:
Potter, Barry, 2007. Therapeutics. A61K31/452-WO2007132179 (A2), 22 November 2007.
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Abstract
The present invention relates to the use of a compound of formula (1) wherein: R1 comprises a carbonyl group and R2 is a hydrocarbyl group; optionally wherein said ring is further substituted; or a pharmaceutically acceptable salt thereof; in the manufacture of a medicament for use in one or more of: modulating the release of intracellular calcium from a store controlled by nicotinic acid adenine dinucleotide phosphate; modulating calcium spikes in mammalian cells; treating diseases in one or more of brain, heart, pancreatic cells (e.g. pancreatic acinar and pancreatic beta cells), immune cells, T-cells, haemopoietic cells including phagocytes; treating diseases in one or more of brain, heart, pancreatic cells (e.g. pancreatic acinar and pancreatic beta cells), immune cells, T-cells, haemopoietic cells including phagocytes by modulating the release of intracellular calcium from a store controlled by nicotinic acid adenine dinucleotide phosphate; treating diseases in one or more of brain, heart, and T-cells by modulating calcium spikes in mammalian cells.
Details
| Item Type | Patent |
| Creators | Potter, B., Dowden, J., Galione, A., Guse, A. H. and Alexander, F. |
| Uncontrolled Keywords | 452 |
| Departments | Faculty of Science > Pharmacy & Pharmacology |
| Status | Published |
| ID Code | 30749 |
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