Transdifferentiation of Cells and Tissues


Slack, J., Horb, M. and Tosh, D., 2003. Transdifferentiation of Cells and Tissues. C07K14/035-WO03078636 (A1), 25 September 2003.

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Method for carrying out transdifferentiation of non-pancreatic cells to pancreatic cells involving the provision of a pancreas specific transcription factor and an activating means such as VP16 of Herpes simplex virus to non-pancreatic cells. The methods and materials provided by the invention may be used to treat pancreatic disorders, in particular disorders caused by a loss of properly functioning pancreas such as pancreatic cancer and diabetes.


Item Type Patent
CreatorsSlack, J., Horb, M. and Tosh, D.
Uncontrolled Keywords035
DepartmentsFaculty of Science > Biology & Biochemistry
ID Code30963


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