Compounds with a Sulfamate Group

Reference:

Reed, Michael J, 1997. Compounds with a Sulfamate Group. A61K31/00-WO9732872 (A1), 12 September 1997.

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Abstract

A sulphamate compound is described. The compound is suitable for use as an inhibitor of both oestrone sulphatase activity and aromatase activity. A preferred compound has general formula (II) wherein F represents a phenolic ring structure (the first ring structure), J represents the third ring structure, I represents a phenolic ring structure (the second ring structure), G is an optional double bond, H is a link joining the second ring structure to the third ring structure, and Y represents a suitable second group; wherein any one of ring structures F, J and I has bound thereto a sulphamate group.

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