Bacteriostatic activity of fluoro-analogues of 5-(2-hydroxyethyl)-4-methylthiazole, a metabolic intermediate in the biosynthesis of thiamine

Reference:

Lowe, G. and Potter, B., 1980. Bacteriostatic activity of fluoro-analogues of 5-(2-hydroxyethyl)-4-methylthiazole, a metabolic intermediate in the biosynthesis of thiamine. Journal of the Chemical Society: Perkin Transactions 1, 1980, pp. 2026-2028.

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Official URL:

http://dx.doi.org/10.1039/P19800002026

Abstract

2-Fluoro-5-(2-hydroxyethyl)-4-methylthiazole and 5-(2-fluoroethyl)-4-methylthiazole have been prepared and the latter converted into a fluoro-analogue of thiamine. All three compounds show bacteriostatic activity against E. coli.

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