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The rise and fall of deleterious mutation


Reference:

Balbi, K. J. and Feil, E. J., 2007. The rise and fall of deleterious mutation. Research in Microbiology, 158 (10), pp. 779-786.

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Abstract

It is well established that selection is less efficient in small populations than in large ones. Here we review the impact of this effect by considering the gradual selective purging of deleterious mutation over time. We Outline an approach to explore the dynamics of this process, and highlight its profound implications. (c) 2007 Elsevier Masson SAS. All rights reserved.

Details

Item Type Articles
CreatorsBalbi, K. J.and Feil, E. J.
DOI10.1016/j.resmic.2007.09.005
DepartmentsFaculty of Science > Biology & Biochemistry
RefereedYes
StatusPublished
ID Code3601
Additional InformationID number: ISI:000252370300007

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