The rise and fall of deleterious mutation
Balbi, K. J. and Feil, E. J., 2007. The rise and fall of deleterious mutation. Research in Microbiology, 158 (10), pp. 779-786.
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It is well established that selection is less efficient in small populations than in large ones. Here we review the impact of this effect by considering the gradual selective purging of deleterious mutation over time. We Outline an approach to explore the dynamics of this process, and highlight its profound implications. (c) 2007 Elsevier Masson SAS. All rights reserved.
|Creators||Balbi, K. J.and Feil, E. J.|
|Departments||Faculty of Science > Biology & Biochemistry|
|Additional Information||ID number: ISI:000252370300007|
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