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Rapid selection for ivermectin resistance in Haemonchus contortus


Reference:

Coles, G. C., Rhodes, A. C. and Wolstenholme, A., 2005. Rapid selection for ivermectin resistance in Haemonchus contortus. Veterinary Parasitology, 129 (3-4), pp. 345-347.

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Abstract

Lambs infected with two isolates, one British and one American, of Haemonchus contortus were treated with increasing doses of ivermectin. Eggs from the highest dose that had not eliminated the infection were cultured and larvae used to infect another lamb. After three generations the H. contortus was resistant to 0.2 mg/kg ivermectin. The results stress the ease with which ivermectin resistance can be selected if high selection pressure is applied. (c) 2005 Elsevier B.V. All rights reserved.

Details

Item Type Articles
CreatorsColes, G. C., Rhodes, A. C. and Wolstenholme, A.
DOI10.1016/j.vetpar.2005.02.002
DepartmentsFaculty of Science > Biology & Biochemistry
RefereedYes
StatusPublished
ID Code3848
Additional InformationID number: ISI:000229303200020

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