Invertebrates as a source of emerging human pathogens
Waterfield, N. R., Wren, B. W. and ffrench-Constant, R. H., 2004. Invertebrates as a source of emerging human pathogens. Nature Reviews Microbiology, 2 (10), pp. 833-841.
Related documents:This repository does not currently have the full-text of this item.
You may be able to access a copy if URLs are provided below.
Despite their importance, little is known about the origins of many emerging human pathogens. However, given the age and current predominance of invertebrates, it is likely that bacteria-invertebrate interactions are not only a present source of human pathogens but have also shaped their evolution. Pathogens of invertebrate and unicellular organisms represent an extensive reservoir of bacterial strains equipped with virulence factors that evolved to overcome the innate immune responses of their hosts. This reservoir might represent a source of new human pathogenic strains and might also foster the spread of novel virulence factors into existing human commensal or pathogenic bacteria. This article examines the available evidence for this concept by examining pairs of closely related bacteria, one of which is benign, but insect associated, and one of which is a human pathogen.
|Creators||Waterfield, N. R., Wren, B. W. and ffrench-Constant, R. H.|
|Departments||Faculty of Science > Biology & Biochemistry|
Actions (login required)