Research

Multilocus sequence typing - what is resolved?


Reference:

Cooper, J. E. and Feil, E. J., 2004. Multilocus sequence typing - what is resolved? Trends in Microbiology, 12 (8), pp. 373-377.

Related documents:

This repository does not currently have the full-text of this item.
You may be able to access a copy if URLs are provided below.

Abstract

Nucleotide sequence-based methods for bacterial typing (multilocus sequence typing; MLST) allow rapid and global comparisons between results from different laboratories. Combining this advantage with the reduced cost of high throughput sequencing, increasing automation and the amenability of sequence data for evolutionary analysis, it seems inevitable that sequence-based typing will eventually predominate over gel-based methods such as pulsed-field gel electrophoresis (PFGE) for most bacterial species. The increasing availability of multiple genome sequences for single pathogenic species, and the recent development of many new MLST schemes, means that a re-examination of the utility of multilocus sequencing, and in particular the choice of gene loci, is now appropriate.

Details

Item Type Articles
CreatorsCooper, J. E.and Feil, E. J.
DOI10.1016/j.tim.2004.06.003
DepartmentsFaculty of Science > Biology & Biochemistry
RefereedYes
StatusPublished
ID Code3990
Additional InformationID number: ISI:000223416600005

Export

Actions (login required)

View Item