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"Click-fluors": Modular fluorescent saccharide sensors based on a 1,2,3-triazole ring


Reference:

Scrafton, D. K., Taylor, J. E., Mahon, M. F., Fossey, J. S. and James, T. D., 2008. "Click-fluors": Modular fluorescent saccharide sensors based on a 1,2,3-triazole ring. Journal of Organic Chemistry, 73 (7), pp. 2871-2874.

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Official URL:

http://dx.doi.org/10.1021/jo702584u

Abstract

A carbohydrate sensing "click-fluor" is reported which displays a nontypical binding preference with sample saccharides. That a fluorescent sensor is generated as a result of triazole formation (click reaction), rather than simply bringing the sensor and reporter units together via a triazole linkage, and the potential applicability of the wide range of easily accessible acetylene units means a simple strategy for the development of modular fluorescent sensor arrays for rapid screening of target saccharides will be available.

Details

Item Type Articles
CreatorsScrafton, D. K., Taylor, J. E., Mahon, M. F., Fossey, J. S. and James, T. D.
DOI10.1021/jo702584u
DepartmentsFaculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code4464
Additional InformationID number: ISI:000254544800047

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