"Click-fluors": Modular fluorescent saccharide sensors based on a 1,2,3-triazole ring
Scrafton, D. K., Taylor, J. E., Mahon, M. F., Fossey, J. S. and James, T. D., 2008. "Click-fluors": Modular fluorescent saccharide sensors based on a 1,2,3-triazole ring. Journal of Organic Chemistry, 73 (7), pp. 2871-2874.
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A carbohydrate sensing "click-fluor" is reported which displays a nontypical binding preference with sample saccharides. That a fluorescent sensor is generated as a result of triazole formation (click reaction), rather than simply bringing the sensor and reporter units together via a triazole linkage, and the potential applicability of the wide range of easily accessible acetylene units means a simple strategy for the development of modular fluorescent sensor arrays for rapid screening of target saccharides will be available.
|Creators||Scrafton, D. K., Taylor, J. E., Mahon, M. F., Fossey, J. S. and James, T. D.|
|Departments||Faculty of Science > Chemistry|
|Additional Information||ID number: ISI:000254544800047|
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