"Click-fluors": Modular fluorescent saccharide sensors based on a 1,2,3-triazole ring

Reference:

Scrafton, D. K., Taylor, J. E., Mahon, M. F., Fossey, J. S. and James, T. D., 2008. "Click-fluors": Modular fluorescent saccharide sensors based on a 1,2,3-triazole ring. Journal of Organic Chemistry, 73 (7), pp. 2871-2874.

Related documents:

Official URL:

http://dx.doi.org/10.1021/jo702584u

Abstract

A carbohydrate sensing "click-fluor" is reported which displays a nontypical binding preference with sample saccharides. That a fluorescent sensor is generated as a result of triazole formation (click reaction), rather than simply bringing the sensor and reporter units together via a triazole linkage, and the potential applicability of the wide range of easily accessible acetylene units means a simple strategy for the development of modular fluorescent sensor arrays for rapid screening of target saccharides will be available.

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