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The effect of the ionophore valinomycin on biomimetic solid supported lipid DPPTE/EPC membranes


Reference:

Rose, L. and Jenkins, A. T. A., 2007. The effect of the ionophore valinomycin on biomimetic solid supported lipid DPPTE/EPC membranes. Bioelectrochemistry, 70 (2), pp. 387-393.

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Abstract

Self assembled monolayers and bilayers are produced on a flat glass surface, bound by a thiolipid onto bare gold. 1,2-Dipalmitoyi-sn-Glycero-3-Phosphothioethanol (DPPTE) is used as the molecule binding to the electrode surface. The lipid lambda-alpha-Phosphatidyi-Choline-beta-Oleoyl-g-Palmiloyl (POPC) and the lipid mixture eggphosphatadiylcholine (EPC) are used as spacer lipids with the aim of achieving solid-supported artificial lipid membranes. With the aim of creating and investigating more natural systems, ion carrier proteins such as valinomycin are introduced into the DPPTE/EPC system. The direct influence on the membranes as well as the effects of different ionic solutions on the proteins is shown. (c) 2006 Elsevier B.V. All rights reserved.

Details

Item Type Articles
CreatorsRose, L.and Jenkins, A. T. A.
DOI10.1016/j.bioelechem.2006.05.009
DepartmentsFaculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code4541
Additional InformationID number: ISI:000246254500029

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