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Ruthenium-catalysed synthesis of tertiary amines from alcohols


Reference:

Haniti, M., Hamid, S. A. and Williams, J. M. J., 2007. Ruthenium-catalysed synthesis of tertiary amines from alcohols. Tetrahedron Letters, 48 (47), pp. 8263-8265.

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Abstract

Secondary amines have been converted into tertiary amines by reactions with primary alcohols. A catalytic system of [Ru(cymene)Cl-2](2) with dppf has been shown to be effective for this transformation for a range of primary alcohols and secondary amines. The methodology has been applied to the one pot synthesis of Piribedil and other piperazine and morpholine-containing products. (C) 2007 Elsevier Ltd. All rights reserved.

Details

Item Type Articles
CreatorsHaniti, M., Hamid, S. A. and Williams, J. M. J.
DOI10.1016/j.tetlet.2007.09.134
DepartmentsFaculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code4600
Additional InformationID number: ISI:000252097200001

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