Research

Simple protocol for NMR analysis of the enantiomeric purity of diols


Reference:

Kelly, A. M., Perez-Fuertes, Y., Arimori, S., Bull, S. D. and James, T. D., 2006. Simple protocol for NMR analysis of the enantiomeric purity of diols. Organic Letters, 8 (10), pp. 1971-1974.

Related documents:

This repository does not currently have the full-text of this item.
You may be able to access a copy if URLs are provided below.

Abstract

A practically simple three-component chiral derivatization protocol for determining the enantiopurity of chiral 1,2-, 1,3-, and 1,4-diols by H-1 NMR spectroscopic analysis is described. The method involves treatment with 2-formylphenylboronic acid and enantiopure alpha-methylbenzylamine to afford a mixture of diastereolsomeric iminoboronate esters whose ratio is an accurate reflection of the enantiopurity of the parent diol.

Details

Item Type Articles
CreatorsKelly, A. M., Perez-Fuertes, Y., Arimori, S., Bull, S. D. and James, T. D.
DOI10.1021/ol0602351
DepartmentsFaculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code4694
Additional InformationID number: ISI:000237420200003

Export

Actions (login required)

View Item