An efficient synthesis of semiplenamide C
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Semiplenamides are anandamide-like fatty acid amide metabolites previously isolated from a marine cyanobacterium that display a range of biological activity. Novel syn-aldol/dehydration methodology has been developed for the stereoselective synthesis of the core (E)-alpha, beta-unsaturated amide functionality of this class of natural product, and employed for the efficient synthesis of semi-plenamide C. (c) 2005 Elsevier Ltd. All rights reserved.
|Creators||Davies, I. R., Cheeseman, M., Niyadurupola, D. G. and Bull, S. D.|
|Departments||Faculty of Science > Chemistry|
|Additional Information||ID number: ISI:000230879300027|
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