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An efficient synthesis of semiplenamide C


Reference:

Davies, I. R., Cheeseman, M., Niyadurupola, D. G. and Bull, S. D., 2005. An efficient synthesis of semiplenamide C. Tetrahedron Letters, 46 (33), pp. 5547-5549.

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Abstract

Semiplenamides are anandamide-like fatty acid amide metabolites previously isolated from a marine cyanobacterium that display a range of biological activity. Novel syn-aldol/dehydration methodology has been developed for the stereoselective synthesis of the core (E)-alpha, beta-unsaturated amide functionality of this class of natural product, and employed for the efficient synthesis of semi-plenamide C. (c) 2005 Elsevier Ltd. All rights reserved.

Details

Item Type Articles
CreatorsDavies, I. R., Cheeseman, M., Niyadurupola, D. G. and Bull, S. D.
DOI10.1016/j.tetlet.2005.06.027
DepartmentsFaculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code4826
Additional InformationID number: ISI:000230879300027

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