A practical synthesis of enantiopure (S)-4-(4-hydroxybenzyl)-oxazolidin-2-one
Green, R., Taylor, P. J. M., Bull, S. D., James, T. D., Mahon, M. F. and Merritt, A. T., 2003. A practical synthesis of enantiopure (S)-4-(4-hydroxybenzyl)-oxazolidin-2-one. Tetrahedron: Asymmetry, 14 (17), pp. 2619-2623.
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A high yielding four-step synthesis of enantiopure 4-(4-hydroxybenzyl)-oxazolidin-2-one (S)-1 from N-Boc-L-tyrosine is described. (S)-1 is a key intermediate for the preparation of a number of polymer supported Evans' oxazolidin-2-ones that have been employed previously for solid supported asymmetric synthesis. (C) 2003 Elsevier Ltd. All rights reserved.
|Creators||Green, R., Taylor, P. J. M., Bull, S. D., James, T. D., Mahon, M. F. and Merritt, A. T.|
|Departments||Faculty of Science > Chemistry|
|Additional Information||ID number: ISI:000185311200020|
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