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An (E)-selective synthesis of trisubstituted (E)-alpha,beta-unsaturated acid derivatives


Reference:

Feuillet, F. J. P., Robinson, D. and Bull, S. D., 2003. An (E)-selective synthesis of trisubstituted (E)-alpha,beta-unsaturated acid derivatives. Chemical Communications

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Abstract

Potassium alkoxides of N-acyloxazolidin-2-one derived syn-aldolates undergo a novel tandem intramolecular cyclisation elimination reaction to afford trisubstituted( E)-alpha,beta-unsaturated amides in high d.e., which may be converted into their corresponding acids or oxazolines in good yield.

Details

Item Type Articles
CreatorsFeuillet, F. J. P., Robinson, D. and Bull, S. D.
DOI10.1039/b304213h
DepartmentsFaculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code5026
Additional InformationID number: ISI:000184684500039

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