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Racemic auxiliaries: applications to asymmetric synthesis


Reference:

Neri, C. and Williams, J. M. J., 2002. Racemic auxiliaries: applications to asymmetric synthesis. Tetrahedron Letters, 43 (23), pp. 4257-4260.

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Abstract

Racemic auxiliaries have been successfully used to achieve asymmetric synthesis. Racemic Evans aldol products were obtained from racemic acyl oxazolidinones with good diastereocontrol. The enantiomers of the racemic aldol products were resolved by a lipase-catalysed acylation reaction. Hydrolysis afforded enantiomerically enriched oxazolidinones and enantiomerically enriched beta-hydroxy acids. (C) 2002 Published by Elsevier Science Ltd.

Details

Item Type Articles
CreatorsNeri, C.and Williams, J. M. J.
DepartmentsFaculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code5110
Additional InformationID number: ISI:000176083000033

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