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A practical asymmetric synthesis of homochiral alpha-arylglycines


Reference:

Mellin-Morliere, C., Aitken, D. J., Bull, S. D., Davies, S. G. and Husson, H. P., 2001. A practical asymmetric synthesis of homochiral alpha-arylglycines. Tetrahedron: Asymmetry, 12 (1), pp. 149-155.

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Abstract

Enantioselective reduction of a series of substituted aryl trichloromethyl ketones with the CBS-catecholborane reagent afforded homochiral aryl trichloromethyl carbinols which have been elaborated to give homochiral alpha -arylglycines in high e.e. (C) 2001 Elsevier Science Ltd. All rights reserved.

Details

Item Type Articles
CreatorsMellin-Morliere, C., Aitken, D. J., Bull, S. D., Davies, S. G. and Husson, H. P.
DepartmentsFaculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code5197
Additional InformationID number: ISI:000167494000022

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