Chemical modification of mammalian cell surfaces


Kellam, B., De Bank, P. A. and Shakesheff, K. M., 2003. Chemical modification of mammalian cell surfaces. Chemical Society Reviews, 32 (6), pp. 327-337.

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Official URL: 10.1039/B211643J


The mammalian cell surface is a highly heterogeneous chemical environment with proteins, carbohydrates, lipids and composite molecules controlling vital cell functions. Chemical modification of this environment is a challenge due to the complexity of the surface chemistry and the fragility of the cell. Here, we review recent attempts to perform targeted, non-genetically controlled, changes to cell surface chemistry. Potential applications of cell surface engineering are presented.


Item Type Articles
CreatorsKellam, B., De Bank, P. A. and Shakesheff, K. M.
DepartmentsFaculty of Science > Pharmacy & Pharmacology
Research CentresCentre for Regenerative Medicine
ID Code7359


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