Chemical modification of mammalian cell surfaces


Barrie, K., Paul, A. D. B. and Kevin, M. S., 2003. Chemical modification of mammalian cell surfaces. Chemical Society Reviews, 32, 327--337.

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The mammalian cell surface is a highly heterogeneous chemical environment with proteins, carbohydrates, lipids and composite molecules controlling vital cell functions. Chemical modification of this environment is a challenge due to the complexity of the surface chemistry and the fragility of the cell. Here, we review recent attempts to perform targeted, non-genetically controlled, changes to cell surface chemistry. Potential applications of cell surface engineering are presented.


Item Type Articles
CreatorsBarrie, K., Paul, A. D. B. and Kevin, M. S.
DepartmentsFaculty of Science > Mathematical Sciences
ID Code7359


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