Chemical modification of mammalian cell surfaces
Kellam, B., De Bank, P. A. and Shakesheff, K. M., 2003. Chemical modification of mammalian cell surfaces. Chemical Society Reviews, 32 (6), pp. 327-337.
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The mammalian cell surface is a highly heterogeneous chemical environment with proteins, carbohydrates, lipids and composite molecules controlling vital cell functions. Chemical modification of this environment is a challenge due to the complexity of the surface chemistry and the fragility of the cell. Here, we review recent attempts to perform targeted, non-genetically controlled, changes to cell surface chemistry. Potential applications of cell surface engineering are presented.
|Creators||Kellam, B., De Bank, P. A. and Shakesheff, K. M.|
|Departments||Faculty of Science > Pharmacy & Pharmacology|
|Research Centres||Centre for Regenerative Medicine|
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