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Chemical modification of mammalian cell surfaces


Reference:

Kellam, B., De Bank, P. A. and Shakesheff, K. M., 2003. Chemical modification of mammalian cell surfaces. Chemical Society Reviews, 32 (6), pp. 327-337.

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Official URL:

http://dx.doi.org/: 10.1039/B211643J

Abstract

The mammalian cell surface is a highly heterogeneous chemical environment with proteins, carbohydrates, lipids and composite molecules controlling vital cell functions. Chemical modification of this environment is a challenge due to the complexity of the surface chemistry and the fragility of the cell. Here, we review recent attempts to perform targeted, non-genetically controlled, changes to cell surface chemistry. Potential applications of cell surface engineering are presented.

Details

Item Type Articles
CreatorsKellam, B., De Bank, P. A. and Shakesheff, K. M.
DOI10.1039/B211643J
DepartmentsFaculty of Science > Pharmacy & Pharmacology
Research CentresCentre for Regenerative Medicine
RefereedYes
StatusPublished
ID Code7359

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