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Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate gives rapid access to precursors for second messenger analogues


Reference:

Riley, A. M., Godage, H. Y., Mahon, M. F. and Potter, B. V. L., 2006. Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate gives rapid access to precursors for second messenger analogues. Tetrahedron: Asymmetry, 17 (2), pp. 171-174.

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Official URL:

http://dx.doi.org/10.1016/j.tetasy.2005.12.008

Abstract

Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate via the formation of diastereoisomeric bis[(1S)-(-)-camphanate] esters provides a convenient and fast route to precursors for biologically important inositol phosphates and lipids, and to synthetic analogues and probes modified at O-1 or O-3 of the inositol ring.

Details

Item Type Articles
CreatorsRiley, A. M., Godage, H. Y., Mahon, M. F. and Potter, B. V. L.
DOI10.1016/j.tetasy.2005.12.008
DepartmentsFaculty of Science > Pharmacy & Pharmacology
Faculty of Science > Chemistry
RefereedYes
StatusPublished
ID Code7695

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