Visualization of the crystallization of lactose from the amorphous state
Price, R. and Young, P. M., 2004. Visualization of the crystallization of lactose from the amorphous state. Journal of Pharmaceutical Sciences, 93 (1), pp. 155-164.
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The physical stability and solid-state recrystallization of spray-dried 'amorphous' lactose particles were visualized using environmentally controlled atomic force microscopy (EC-AFM) and conventional optical microscopy. The morphology and crystalline state were investigated as a function of relative humidity (RH) and were correlated with bulk gravimetric vapor sorption measurements that were run in parallel. The metastable nature of amorphous spray-dried lactose particles was apparent at low RHs (
|Creators||Price, R.and Young, P. M.|
|Departments||Faculty of Science > Pharmacy & Pharmacology|
|Additional Information||ID number: ISI:000187668400017|
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