Visualization of the crystallization of lactose from the amorphous state
Reference:
Price, R. and Young, P. M., 2004. Visualization of the crystallization of lactose from the amorphous state. Journal of Pharmaceutical Sciences, 93 (1), pp. 155-164.
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Abstract
The physical stability and solid-state recrystallization of spray-dried 'amorphous' lactose particles were visualized using environmentally controlled atomic force microscopy (EC-AFM) and conventional optical microscopy. The morphology and crystalline state were investigated as a function of relative humidity (RH) and were correlated with bulk gravimetric vapor sorption measurements that were run in parallel. The metastable nature of amorphous spray-dried lactose particles was apparent at low RHs (
Details
| Item Type | Articles |
| Creators | Price, R.and Young, P. M. |
| DOI | 10.1002/jps.10513 |
| Departments | Faculty of Science > Pharmacy & Pharmacology |
| Refereed | Yes |
| Status | Published |
| ID Code | 8021 |
| Additional Information | ID number: ISI:000187668400017 |
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