Research

Items by Wonnacott, Susan

Up a level
Export as [feed] RSS 1.0 [feed] Atom [feed] RSS 2.0
Group by: Item Type | Date | No Grouping
Jump to: 2014 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1996 | 1995 | 1994
Number of items: 103.

2014

Brown, J. L. and Wonnacott, S., 2014. Forthcoming. Sazetidine-A Activates and Desensitizes Native α7 Nicotinic Acetylcholine Receptors. Neurochemical Research

2012

Bennett, H. M., Lees, K., Harper, K. M., Jones, A. K., Sattelle, D. B., Wonnacott, S. and Wolstenholme, A. J., 2012. Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes. Journal of Neurochemistry, 123 (6), pp. 911-918.

Kennett, A., Heal, D. J. and Wonnacott, S., 2012. Pharmacological differences between rat frontal cortex and hippocampus in the nicotinic modulation of noradrenaline release implicate distinct receptor subtypes. Nicotine & Tobacco Research, 14 (11), nts128.

2011

Quik, M. and Wonnacott, S., 2011. α6β2* and α4β2* Nicotinic Acetylcholine Receptors As Drug Targets for Parkinson's Disease. Pharmacological Reviews, 63 (4), pp. 938-966.

del Barrio, L., Martin-de-Saavedra, M. D., Romero, A., Parada, E., Egea, J., Avila, J., McIntosh, J. M., Wonnacott, S. and Lopez, M. G., 2011. Neurotoxicity Induced by Okadaic Acid in the Human Neuroblastoma SH-SY5Y Line Can Be Differentially Prevented by alpha 7 and beta 2*Nicotinic Stimulation. Toxicological Sciences, 123 (1), pp. 193-205.

Glendinning, S. K., Buckingham, S. D., Sattelle, D. B., Wonnacott, S. and Wolstenholme, A. J., 2011. Glutamate-Gated Chloride Channels of Haemonchus contortus Restore Drug Sensitivity to Ivermectin Resistant Caenorhabditis elegans. PLoS ONE, 6 (7), e22390.

2010

Iturriaga-Vasquez, P., Carbone, A., Garcia-Beltran, O., Livingstone, P. D., Biggin, P. C., Cassels, B. K., Wonnacott, S., Zapata-Torres, G. and Bermudez, I., 2010. Molecular determinants for competitive inhibition of alpha 4 beta 2 nicotinic acetylcholine receptors. Molecular Pharmacology, 78 (3), pp. 366-375.

Innocent, N., Evans, N., Hille, C. and Wonnacott, S., 2010. Oligomerisation differentially affects the acute and chronic actions of amyloid-β in vitro. Neuropharmacology, 59 (4-5), pp. 343-352.

Kennett, A. F., Heal, D. and Wonnacott, S., 2010. Investigating the subtypes of nocotinic achr involved incatecholamine release in different regions of the rodent brain. Journal of Psychopharmacology, 24 (Supplement 3), A32.

Wonnacott, S. and Livingstone, P. D., 2010. Nicotinic receptors and the modulation of transmitter release in the prefrontal cortex. European Neuropsychopharmacology, 20 (Supplement 3), S193.

Araud, T., Wonnacott, S. and Bertrand, D., 2010. Associated proteins: the universal toolbox controlling ligand gated ion channel function. Biochemical Pharmacology, 80 (2), pp. 160-169.

Abin-Carriquiry, J. A., Zunini, M. P., Cassels, B. K., Wonnacott, S. and Dajas, F., 2010. In silico characterization of cytisinoids docked into an acetylcholine binding protein. Bioorganic & Medicinal Chemistry Letters, 20 (12), pp. 3683-3687.

Livingstone, P. D., Dickinson, J. A., Srinivasan, J., Kew, J. N. C. and Wonnacott, S., 2010. Glutamate-Dopamine Crosstalk in the Rat Prefrontal Cortex is Modulated by Alpha7 Nicotinic Receptors and Potentiated by PNU-120596. Journal of Molecular Neuroscience, 40 (1-2), pp. 172-176.

Abin-Carriquiry, J. A., Urbanavicius, J., Scorza, C., Rebolledo-Fuentes, M., Wonnacott, S., Cassels, B. K. and Dajas, F., 2010. Increase in locomotor activity after acute administration of the nicotinic receptor agonist 3-bromocytisine in rats. European Journal of Pharmacology, 634 (1-3), pp. 89-94.

Rushforth, S. L., Allison, C., Wonnacott, S. and Shoaib, M., 2010. Subtype-selective nicotinic agonists enhance olfactory working memory in normal rats: A novel use of the odour span task. Neuroscience Letters, 471 (2), pp. 114-118.

2009

Kennett, A., Heal, D. and Wonnacott, S., 2009. Distinct pharmacological profiles for nicotinic AChR-evoked noradrenaline release in rat frontal cortex and hippocampus. Biochemical Pharmacology, 78 (7), pp. 915-916.

Livingstone, P. D., Hockley, J. and Wonnacott, S., 2009. Nicotinic acetylcholine receptors differentially regulate phosphorylation of dopamine target cell proteins in the rat prefrontal cortex. Biochemical Pharmacology, 78 (7), p. 909.

Livingstone, P. D. and Wonnacott, S., 2009. Nicotinic acetylcholine receptors and the ascending dopamine pathways. Biochemical Pharmacology, 78 (7), pp. 744-755.

Quarta, D., Naylor, C. G., Barik, J., Fernandes, C., Wonnacott, S. and Stolerman, I. P., 2009. Drug discrimination and neurochemical studies in alpha 7 null mutant mice: tests for the role of nicotinic alpha 7 receptors in dopamine release. Psychopharmacology, 203 (2), pp. 399-410.

Livingstone, P. D., Srinivasan, J., Kew, J. N. C., Dawson, L. A., Gotti, C., Moretti, M., Shoaib, M. and Wonnacott, S., 2009. α7 and non-α7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex. European Journal of Neuroscience, 29 (3), pp. 539-550.

Barik, J. and Wonnacott, S., 2009. Molecular and cellular mechanisms of action of nicotine in the CNS. In: Henningfield, J. E., London, E. D. and Pogun, S., eds. Nicotine Psychopharmacology. Vol. 192. Berlin: Springer, pp. 173-207. (Handbook of Experimental Pharmacology)

2008

Innocent, N., Livingstone, P. D., Hone, A., Kimura, A., Young, T., Whiteaker, P., McIntosh, J. M. and Wonnacott, S., 2008. Aplha-Conotoxin Arenatus IB[V11L,V16D] Is a Potent and Selective Antagonist at Rat and Human Native 7 Nicotinic Acetylcholine Receptors. Journal of Pharmacology and Experimental Therapeutics, 327 (2), pp. 529-537.

Dickinson, J. A., Kew, J. N. C. and Wonnacott, S., 2008. Presynaptic α7- and β2-containing nicotinic acetylcholine receptors modulate excitatory amino acid release from rat prefrontal cortex nerve terminals via distinct cellular mechanisms. Molecular Pharmacology, 74 (2), pp. 348-359.

Abin-Carriquiry, J., Costa, G., Urbanavicius, J., Cassels, B., Rebolledo-Fuentes, M., Wonnacott, S. and Dajas, F., 2008. In vivo modulation of dopaminergic nigrostriatal pathways by cytisine derivatives: Implications for Parkinson's Disease. European Journal of Pharmacology, 589 (1-3), pp. 80-84.

Wonnacott, S., 2008. Smoking cessation 2008. IDrugs, 11 (4), pp. 256-259.

Hanrott, K., Murray, T. K., Orfali, Z., Ward, M., Finlay, C., O'Neill, M. J. and Wonnacott, S., 2008. Differential activation of PKCδ in the substantia nigra of rats following striatal or nigral 6-hydroxydopamine lesions. European Journal of Neuroscience, 27 (5), pp. 1086-1096.

Wonnacott, S., 2008. Gates and filters: unveiling the physiological roles of nicotinic acetylcholine receptors in dopaminergic transmission. British Journal of Pharmacology, 153 (S1), S2-S4.

2007

Dickinson, J. A., Kew, J. N. C., Nairn, A. C. and Wonnacott, S., 2007. Cellular mechanisms coupling alpha 7 nicotinic acetylcholine receptors to neurotransmitter release in PFC synaptosomes: Involvement of Ca2+-induced Ca2+ release; ERKI/2 and synapsin-1 phosphorylation. Biochemical Pharmacology, 74 (8), SMA16-SMA17.

Oliver, J. L., Pashmi, G., Barnett, P., Mettens, P., Biemans, R., Monteyne, P., Palmantier, R., Gallagher, T., Ramaya, S. and Wonnacott, S., 2007. Development of an anti-cotinine vaccine to potentiate nicotine-based smoking cessation strategies. Vaccine, 25 (42), pp. 7354-7362.

Urbanavicius, J., Margot, F., Costa, G., Abin, J.-A., Wonnacott, S. and Dajas, F., 2007. Intermittent nicotine administration selectively induced tyrosine hydroxylase plasticity in the neurodegenerating striatum. Journal of Neurochemistry, 102 (3), pp. 723-730.

Sidhpura, N., Reffern, P. and Wonnacott, S., 2007. Comparison of the effects of bupropion on nicotinic receptor-evoked [(3) H]dopamine release from rat striatal synaptosomes and slices. European Journal of Pharmacology, 567 (1-2), pp. 102-109.

Dickinson, J. A., Hanrott, K. E., Mok, M. H. S., Kew, J. N. C. and Wonnacott, S., 2007. Differential coupling of alpha 7 and non-alpha 7 nicotinic acetylcholine receptors to calcium-induced calcium release and voltage-operated calcium channels in PC12 cells. Journal of Neurochemistry, 100 (4), pp. 1089-1096.

Nuutinen, S., Barik, J., Jones, I. W. and Wonnacott, S., 2007. Differential effects of acute and chronic nicotine on Elk-I in rat hippocampus. Neuroreport, 18 (2), pp. 121-126.

Sidhpura, N., Redfern, P., Rowley, H., Heal, D. and Wonnacott, S., 2007. Comparison of the effects of bupropion and nicotine on locomotor activation and dopamine release in vivo. Biochemical Pharmacology, 74 (8), pp. 1292-1298.

Wonnacott, S. and Barik, J., 2007. Nicotinic ACh Receptors. Tocris Reviews, 28.

2006

Kanakubo, A., Gray, D., Innocent, N., Wonnacott, S. and Gallagher, T., 2006. The synthesis and nicotinic binding activity of (+/-)-epiquinamide and (+/-)C(1)-epiepiquinamide. Bioorganic & Medicinal Chemistry Letters, 16 (17), pp. 4648-4651.

Abin-Carriquiry, J. A., Voutilainen, M. H., Barik, J., Cassels, B. K., Iturriaga-Vasquez, P., Bermudez, I., Durand, C., Dajas, F. and Wonnacott, S., 2006. C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists. European Journal of Pharmacology, 536 (1-2), pp. 1-11.

Wonnacott, S. and Gallagher, T., 2006. The chemistry and pharmacology of anatoxin-a and related homotropanes with respect to nicotinic acetylcholine receptors. Marine Drugs, 4 (3), pp. 228-254.

Hanrott, K., Gudmunsen, L., O'Neill, M. J. and Wonnacott, S., 2006. d6-Hydroxydopamine- induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase C delta. Journal of Biological Chemistry, 281 (9), pp. 5373-5382.

Barik, J. and Wonnacott, S., 2006. Indirect modulation by alpha 7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices: Interaction with glutamate and GABA systems and effect of nicotine withdrawal. Molecular Pharmacology, 69 (2), pp. 618-628.

Wonnacott, S., Barik, J., Dickinson, J. and Jones, I. W., 2006. Nicotinic receptors modulate transmitter cross talk in the CNS. Journal of Molecular Neuroscience, 30 (1-2), pp. 137-140.

Jones, I. W., Westmacott, A., Chan, E., Jones, R. W., Dineley, K., O'Neill, M. J. and Wonnacott, S., 2006. alpha 7 nicotinic acetylcholine receptor expression in Alzheimer's disease - Receptor densities in brain regions of the APP((SWE)) mouse model and in human peripheral blood lymphocytes. Journal of Molecular Neuroscience, 30 (1-2), pp. 83-84.

2005

Cassels, B. K., Bermudez, I., Dajas, F., Abin-Carriquiry, J. A. and Wonnacott, S., 2005. From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research. Drug Discovery Today, 10 (23-24), pp. 1657-1665.

Barik, J., Dajas-Bailador, F. and Wonnacott, S., 2005. Cellular responses to nicotinic receptor activation are decreased after prolonged exposure to galantamine in human neuroblastoma cells. British Journal of Pharmacology, 145 (8), pp. 1084-1092.

Abin-Carriquiry, J. A., Iturriaga-Vasquez, P., Costa, G., Urbanavicius, J., Ferreira, M., Cassels, B., Wonnacott, S. and Dajas, F., 2005. Cytisine and derivatives partially prevents the striatal dopamine decrease in an experimental model of Parkinson's disease. Journal of Neurochemistry, 94 (Supplement 2), p. 47.

Rousseau, S. J., Jones, I. W., Pullar, I. A. and Wonnacott, S., 2005. Presynaptic alpha 7 and non-alpha 7 nicotinic acetylcholine receptors modulate [H-3]D-aspartate release from rat frontal cortex in vitro. Neuropharmacology, 49 (1), pp. 59-72.

Jones, I. W. and Wonnacott, S., 2005. Why doesn't nicotinic ACh receptor immunoreactivity knock out? Trends in Neurosciences, 28 (7), pp. 343-345.

Wonnacott, S., Sidhpura, N. and Balfour, D. J. K., 2005. Nicotine: from molecular mechanisms to behaviour. Current Opinion in Pharmacology, 5 (1), pp. 53-59.

Barik, J. and Wonnacott, S., 2005. Chronic nicotine use and its withdrawal: Effects on receptor numbers and release of striatal dopamine and hippocampal noradrenaline. Nicotine & Tobacco Research, 7 (4), p. 651.

2004

Jones, I. W. and Wonnacott, S., 2004. Precise localization of alpha 7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area. Journal of Neuroscience, 24 (50), pp. 11244-11252.

Mogg, A. J., Jones, F. A., Pullar, I. A., Sharples, C. G. V. and Wonnacott, S., 2004. Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380. Neuropharmacology, 47 (6), pp. 848-859.

Dajas-Bailador, F. and Wonnacott, S., 2004. Nicotinic acetylcholine receptors and the regulation of neuronal signalling. Trends in Pharmacological Sciences, 25 (6), pp. 317-324.

Nicke, A., Wonnacott, S. and Lewis, R. J., 2004. alpha-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes. European Journal of Biochemistry, 271 (12), pp. 2305-2319.

Jones, I. W., Barik, J., O'Neill, M. J. and Wonnacott, S., 2004. Alpha bungarotoxin-1.4 nm gold: a novel conjugate for visualising the precise subcellular distribution of alpha 7*nicotinic acetylcholine receptors. Journal of Neuroscience Methods, 134 (1), pp. 65-74.

Sidhpura, N., Rowley, H. L., Heal, D. J., Mitchell, P. J., Redfern, P. H. and Wonnacott, S., 2004. Neurochemical interactions of nicotine and bupropion in the rat striatum. Journal of Psychopharmacology, 18 (3), A31.

2003

Hejmadi, M. V., Dajas-Bailador, F., Barns, S. M., Jones, B. and Wonnacott, S., 2003. Neuroprotection by nicotine against hypoxia-induced apoptosis in cortical cultures involves activation of multiple nicotinic acetylcholine receptor subtypes. Molecular and Cellular Neuroscience, 24 (3), pp. 779-786.

Dajas-Bailador, F. A., Heimala, K. and Wonnacott, S., 2003. The allosteric potentiation of nicotinic acetylcholine receptors by galantamine is transduced into cellular responses in neurons: Ca2+ signals and neurotransmitter release. Molecular Pharmacology, 64 (5), pp. 1217-1226.

Karig, G., Large, J. M., Sharples, C. G. V., Sutherland, A., Gallagher, T. and Wonnacott, S., 2003. Synthesis and nicotinic binding of novel phenyl derivatives of UB-165. Identifying factors associated with alpha 7 selectivity. Bioorganic & Medicinal Chemistry Letters, 13 (17), pp. 2825-2828.

Hahn, B., Sharples, C. G. V., Wonnacott, S., Shoaib, M. and Stolerman, P., 2003. Attentional effects of nicotinic agonists in rats. Neuropharmacology, 44 (8), pp. 1054-1067.

Richardson, C. E., Morgan, J. M., Jasani, B., Green, J. T., Rhodes, J., Williams, G. T., Lindstrom, J., Wonnacott, S., Peel, S. and Thomas, G. A. O., 2003. Effect of smoking and transdermal nicotine on colonic nicotinic acetylcholine receptors in ulcerative colitis. QJM: An International Journal of Medicine, 96 (1), pp. 57-65.

Pashmi, G., Barnett, P., Mettens, P., Gallagher, T. and Wonnacott, S., 2003. Immunotherapy approach targeting cotinine, the major metabolite of nicotine, to combat nicotine addiction. Society for Neuroscience Abstracts, 2003, 322.2.

Sutherland, A., Gallagher, T., Sharples, C. G. V. and Wonnacott, S., 2003. Synthesis of two fluoro analogues of the nicotinic acetylcholine receptor agonist UB-165. Journal of Organic Chemistry, 68 (6), pp. 2475-2478.

2002

Wonnacott, S. and Mogg, A., 2002. Chronic nicotine treatment and nicotinic receptor function. European Neuropsychopharmacology, 12 (Supplement 3), S87-S88.

Mogg, A. J., Whiteaker, P., McIntosh, J. M., Marks, M., Collins, A. C. and Wonnacott, S., 2002. Methyllycaconitine is a potent antagonist of alpha-conotoxin-MII-sensitive presynaptic nicotinic acetylcholine receptors in rat striatum. Journal of Pharmacology and Experimental Therapeutics, 302 (1), pp. 197-204.

Hejmadi, M., Barnes, S. and Wonnacott, S., 2002. Role of nicotinic receptors in hypoxia-induced cell death in rat primary cortical cultures. Neurobiology of Aging, 23 (1), S508-S508.

Dajas-Bailador, F. A., Mogg, A. J. and Wonnacott, S., 2002. Intracellular Ca2+ signals evoked by stimulation of nicotinic acetylcholine receptors in SH-SY5Y cells: contribution of voltage-operated Ca2+ channels and Ca2+ stores. Journal of Neurochemistry, 81 (3), pp. 606-614.

Ridley, D. L., Pakkanen, J. and Wonnacott, S., 2002. Effects of chronic drug treatments on increases in intracellular calcium mediated by nicotinic acetylcholine receptors in SH-SY5Y cells. British Journal of Pharmacology, 135 (4), pp. 1051-1059.

Dajas-Bailador, F. A., Soliakov, L. and Wonnacott, S., 2002. Nicotine activates the extracellular signal-regulated kinase 1/2 via the alpha 7 nicotinic acetylcholine receptor and protein kinase A, in SH-SY5Y cells and hippocampal neurones. Journal of Neurochemistry, 80 (3), pp. 520-530.

Sidhpura, N., Kenyon, R., Redfern, P. and Wonnacott, S., 2002. Actions of bupropion on nicotine-evoked dopamine release in rat striatum. Behavioural Pharmacology, 13 (5-6), pp. 503-504.

Rousseau, S., Wonnacott, S. and Pullar, I., 2002. Activation of the presynaptic nicotinic acetylcholine receptor modulates the depolarisation-dependant release of [H-3]D-aspartate from rat frontal cortex synaptosomes. British Journal of Pharmacology, 136.

Jones, I. W., Bolam, J. P. and Wonnacott, S., 2002. Localization of neuronal nicotinic acetylcholine receptor subunits in rat substantia nigra and dorsal striatum. In: Nicholson, L. F. B. and Faull, R. L., eds. Basal Gangia VII. Plenum Press, New York, pp. 127-136.

Sharples, C. G. V., Karig, G., Simpson, G. L., Spencer, J. A., Wright, E., Millar, N. S., Wonnacott, S. and Gallagher, T., 2002. Synthesis and pharmacological characterization of novel analogues of the nicotinic acetylcholine receptor agonist (+/-)-UB-165. Journal of Medicinal Chemistry, 45 (15), pp. 3235-3245.

Da Cunha, C., Angelucci, M. E. M., Canteras, N. S., Wonnacott, S. and Takahashi, R. N., 2002. The lesion of the rat substantia nigra pars compacta dopaminergic neurons as a model for Parkinson's disease memory disabilities. Cellular and Molecular Neurobiology, 22 (3), pp. 227-237.

2001

Jones, I. W., Bolam, J. P. and Wonnacott, S., 2001. Presynaptic localisation of the nicotinic acetylcholine receptor beta 2 subunit immunoreactivity in rat nigrostriatal dopaminergic neurones. The Journal of Comparative Neurology, 439 (2), pp. 235-247.

Wonnacott, S., Mogg, A., Bradly, A. and Jones, I. W., 2001. Presynaptic nicotinic acetylcholine receptors: subtypes mediating neurotransmitter release. In: Levin, E. D., ed. Nicotine Receptors in the Nervous System. CRC Press, pp. 29-50.

Soliakov, L. and Wonnacott, S., 2001. Involvement of protein kinase C in the presynaptic nicotinic modulation of [H-3]-dopamine release from rat striatal synaptosomes. British Journal of Pharmacology, 132 (3), pp. 785-791.

Hodgson, D. M., Maxwell, C. R., Wisedale, R., Matthews, I. R., Carpenter, K. J., Dickenson, A. H. and Wonnacott, S., 2001. 6-Substituted 2-azabicyclo[2.2.1]hept-5-enes by nitrogen-directed radical rearrangement: Synthesis of an epibatidine analogue with high binding affinity at the nicotinic acetylcholine receptor. Journal of the Chemical Society: Perkin Transactions 1

Sharples, C. G. V., Jones, I. W., Millar, N., Karig, G., Gallagher, T. and Wonnacott, S., 2001. Characterisation of UB-165 analogues at the alpha3beta4 nicotinic acetylcholine receptor. Society for Neuroscience Abstracts, 27 (1), p. 1276.

Dajas-Bailador, F. A., Mogg, A. and Wonnacott, S., 2001. Contribution of intracellular stores to the increase in cytoplasmic calcium after nAChR activation in SH-SY5Y cells. Society for Neuroscience Abstracts, 27 (1), p. 987.

Ridley, D. L., Rogers, A. and Wonnacott, S., 2001. Differential effects of chronic drug treatment on alpha 3*and alpha 7 nicotinic receptor binding sites, in hippocampal neurones and SH-SY5Y cells. British Journal of Pharmacology, 133 (8), pp. 1286-1295.

Richardson, C. E., Morgan, J. M., Jasani, B., Green, J. T., Rhodes, J., Williams, G. T., Lindstrom, J., Wonnacott, S., Thomas, G. A. O. and Smith, V., 2001. Megacystis-microcolon-intestinal hypoperistalsis syndrome and the absence of the alpha 3 nicotinic acetylcholine receptor subunit. Gastroenterology, 121 (2), pp. 350-357.

Sharples, C. G. V. and Wonnacott, S., 2001. Neuronal nicotinic receptors. Tocris Reviews, 19.

Wonnacott, S., 2001. Nicotinic receptors in relation to nicotine addiction - Target article on nicotine-addiction. Psycoloquy, 12 (6), pp. 1-7.

Bradly, A. L., Jones, I. W. and Wonnacott, S., 2001. Ultrastructural localisation of neuronal nicotinic acetylcholine receptor alpha4 subunit in rat nigro-striatal neurons. Society for Neuroscience Abstracts, 27 (1), p. 980.

Lind, R. J., Hardick, D. J., Blagbrough, I. S., Potter, B. V. L., Wolstenholme, A. J., Davies, A. R. L., Clough, M. S., Earley, F. G. P., Reynolds, S. E. and Wonnacott, S., 2001. [3H]-methyllycaconitine : a high affinity radioligand that labels invertebrate nicotinic acetylcholine receptors. Insect Biochemistry and Molecular Biology, 31 (6-7), pp. 533-542.

2000

Dajas-Bailador, F. A., Lima, P. A. and Wonnacott, S., 2000. The alpha 7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca2+ dependent mechanism. Neuropharmacology, 39 (13), pp. 2799-2807.

Wonnacott, S., Kaiser, S., Mogg, A., Soliakov, L. and Jones, I. W., 2000. Presynaptic nicotinic receptors modulating dopamine release in the rat striatum. European Journal of Pharmacology, 393 (1-3), pp. 51-58.

Soliakov, L., Patrick, S. and Wonnacott, S., 2000. Co-operation between nicotinic AChR and muscarinic AChR in the modulation of [H-3]dopamine release from rat striatal nerve terminals. British Journal of Pharmacology, 129 (Supplement), U69.

Soliakov, L., Dajas-Bailador, F. and Wonnacott, S., 2000. NAChR-induced activation of MAPK (ERK1/2) in the human neuroblastoma SH-SY5Y cells. European Journal of Neuroscience, 12 (Supplement), p. 35.

Sharples, C. G. V., Kaiser, S., Soliakov, L., Marks, M. J., Collins, A. C., Washburn, M., Wright, E., Spencer, J. A., Gallagher, T., Whiteaker, P. and Wonnacott, S., 2000. UB-165: A novel nicotinic agonist with subtype selectivity implicates the alpha 4 beta 2*subtype in the modulation of dopamine release from rat striatal synaptosomes. Journal of Neuroscience, 20 (8), pp. 2783-2791.

Jones, I. W., Bolam, J. P. and Wonnacott, S., 2000. Ultrastructural localisation of neuronal nicotinic acetylcholine receptor beta 2 subunit and tyrosine hydroxylase in rat striatum. European Journal of Neuroscience, 12 (Supplement), p. 35.

Kaiser, S. and Wonnacott, S., 2000. alpha-Bungarotoxin-sensitive nicotinic receptors indirectly modulate [H-3]dopamine release in rat striatal slices via glutamate release. Molecular Pharmacology, 58 (2), pp. 312-318.

1999

Whiteaker, P., Davies, A. R. L., Marks, M. J., Blagbrough, I. S., Potter, B. V. L., Wolstenholme, A. J., Collins, A. C. and Wonnacott, S., 1999. An autoradiographic study of the distribution of binding sites for the novel ∝7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain. European Journal of Neuroscience, 11 (8), pp. 2689-2696.

Davies, A. R. L., Hardick, D. J., Blagbrough, I. S., Potter, B. V. L., Wolstenholme, A. J. and Wonnacott, S., 1999. Characterisation of the binding of [3H]methyllycaconitine : a new radioligand for labelling α7-type neuronal nicotinic acetylcholine receptors. Neuropharmacology, 38 (5), pp. 679-690.

1998

Doisy, X., Blagbrough, I. S., Wonnacott, S. and Potter, B. V. L., 1998. Design, synthesis and biological evaluation of substituted benzoate analogues of the selective nicotinic acetylcholine receptor antagonist, methyllycaconitine. Pharmacy and Pharmacology Communications, 4 (7), pp. 313-317.

1996

Wonnacott, S., Soliakov, L., Wilkie, G., Redfern, P. and Marshall, D., 1996. Presynaptic nicotinic acetylcholine receptors in the brain. Drug Development Research, 38 (3-4), pp. 149-159.

Hardick, D. J., Blagbrough, I. S., Cooper, G., Potter, B. V. L., Critchley, T. and Wonnacott, S., 1996. Nudicauline and elatine as potent norditerpenoid ligands at rat neuronal α-bungarotoxin binding sites : importance of the 2-(methylsuccinimido)benzoyl moiety for neuronal nicotinic acetylcholine receptor binding. Journal of Medicinal Chemistry, 39 (24), pp. 4860-4866.

Marshall, D., Soliakov, L., Redfern, P. and Wonnacott, S., 1996. Tetrodotoxin-sensitivity of nicotine-evoked dopamine release from rat striatum. Neuropharmacology, 35 (11), pp. 1531-1536.

1995

Hardick, D. J., Cooper, G., Scott-Ward, T., Blagbrough, I. S., Potter, B. V. L. and Wonnacott, S., 1995. Conversion of the sodium channel activator aconitine into a potent α7-selective nicotinic ligand. FEBS Letters, 365 (1), pp. 79-82.

1994

Blagbrough, I. S., Coates, P. A., Hardick, D. J., Lewis, T., Rowan, M. G., Wonnacott, S. and Potter, B. V. L., 1994. Acylation of lycoctonine : semi-synthesis of inuline, delsemine analogues and methyllycaconitine. Tetrahedron Letters, 35 (46), pp. 8705-8708.

Coates, P. A., Blagbrough, I. S., Hardick, D. J., Rowan, M. G., Wonnacott, S. and Potter, B. V. L., 1994. Rapid and efficient isolation of the nicotinic receptor antagonist methyllycaconitine from delphinium : assignment of the methylsuccinimide absolute stereochemistry as S. Tetrahedron Letters, 35 (46), pp. 8701-8704.

Hardick, D. J., Blagbrough, I. S., Wonnacott, S. and Potter, B. V. L., 1994. Regioselective anthranoylation of demethylated aconitine : novel analogues of aconitine inuline and methyllycaconitine. Tetrahedron Letters, 35 (20), pp. 3371-3374.

Blagbrough, I. S., Hardick, D. J., Wonnacott, S. and Potter, B. V. L., 1994. Regioselective demethylation of aconitine. Tetrahedron Letters, 35 (20), pp. 3367-3370.

This list was generated on Fri Oct 24 04:58:02 2014 IST.