Items by Wolstenholme, Adrian

2012

Bennett, H. M., Lees, K., Harper, K. M., Jones, A. K., Sattelle, D. B., Wonnacott, S. and Wolstenholme, A. J., 2012. Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes. Journal of Neurochemistry, 123 (6), pp. 911-918.

Šnábel, V., Königová, A., Dolinská, M., Várady, M. and Wolstenholme, A.J., 2012. Allozyme analysis of Haemonchus contortus resistant and susceptible to anthelmintics, with an indication of dipeptidases associated with resistance. Helminthologia, 49 (3), pp. 128-133.

Bennett, H. M., Williamson, S. M., Walsh, T. K., Woods, D. J. and Wolstenholme, A. J., 2012. ACR-26: A novel nicotinic receptor subunit of parasitic nematodes. Molecular and Biochemical Parasitology, 183 (2), pp. 151-157.

2011

El-Abdellati, A., De Graef, J., Van Zeveren, A., Donnan, A., Skuce, P., Walsh, T., Wolstenholme, A., Tait, A., Vercruysse, J., Claerebout, E. and Geldhof, P., 2011. Altered avr-14B gene transcription patterns in ivermectin-resistant isolates of the cattle parasites, Cooperia oncophora and Ostertagia ostertagi. International Journal for Parasitology, 41 (9), pp. 951-957.

Glendinning, S. K., Buckingham, S. D., Sattelle, D. B., Wonnacott, S. and Wolstenholme, A. J., 2011. Glutamate-Gated Chloride Channels of Haemonchus contortus Restore Drug Sensitivity to Ivermectin Resistant Caenorhabditis elegans. PLoS ONE, 6 (7), e22390.

2010

Yusein, S., Wolstenholme, A. and Semenov, E., 2010. Functional consequences of mutations in the Drosophila histamine receptor HCLB. Journal of Insect Physiology, 56 (1), pp. 21-27.

Dale, R. P., Jones, A. K., Tamborindeguy, C., Davies, T. G. E., Amey, J. S., Williamson, S., Wolstenholme, A., Field, L. M., Williamson, M. S., Walsh, T. K. and Sattelle, D. B., 2010. Identification of ion channel genes in the Acyrthosiphon pisum genome. Insect Molecular Biology, 19 (s2), pp. 141-153.

2009

Mccavera, S., Rogers, A. T., Yates, D. M., Woods, D. J. and Wolstenholme, A. J., 2009. An ivermectin-sensitive glutamate-gated chloride channel from the parasitic nematode haemonchus contortus. Molecular Pharmacology, 75 (6), pp. 1347-1355.

von Samson-Himmelstjerna, G., Walsh, T. K., Donnan, A. A., Carriere, S., Jackson, F., Skuce, P. J., Rohn, K. and Wolstenholme, A. J., 2009. Molecular detection of benzimidazole resistance in Haemonchus contortus using real-time PCR and pyrosequencing. Parasitology, 136 (3), pp. 349-358.

Williamson, S. M., Robertson, A. P., Brown, L., Williams, T., Woods, D. J., Martin, R. J., Sattelle, D. B. and Wolstenholme, A., 2009. The nicotinic acetylcholine receptors of the parasitic nematode ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits. PLoS Pathogens, 5 (7), e1000517.

2007

Sekaran, S., Lall, G. S., Ralphs, K. L., Wolstenholme, A. J., Lucas, R. J., Foster, R. G. and Hankins, M. W., 2007. 2-aminoethoxydiphenylborane is an acute inhibitor of directly photosensitive retinal ganglion cell activity in vitro and in vivo. Journal of Neuroscience, 27 (15), pp. 3981-3986.

Walsh, T. K., Donnan, A. A., Jackson, F., Skuce, P. and Wolstenholme, A. J., 2007. Detection and measurement of benzimidazole resistance alleles in Haemonchus contortus using real-time PCR with locked nucleic acid Taqman probes. Veterinary Parasitology, 144 (3-4), pp. 304-312.

Wolstenholme, A. J., Bowman, A. S. and Sattelle, D. B., 2007. Frontiers in parasitic neurobiology: parasite genomics, neural signalling and new targets for control. Invertebrate Neuroscience, 7, pp. 179-181.

McCavera, S., Walsh, T. K. and Wolstenholme, A. J., 2007. Nematode ligand-gated chloride channels: an appraisal of their involvement in macrocyclic lactone resistance and prospects for developing molecular markers. Parasitology, 134, pp. 1111-1121.

Reaves, B. J. and Wolstenholme, A. J., 2007. The TRP channel superfamily: insights into how structure, protein-lipid interactions and localization influence function. Biochemical Society Transactions, 35, pp. 77-80.

Williamson, S. M., Walsh, T. K. and Wolstenholme, A. J., 2007. The cys-loop ligand-gated ion channel gene family of Brugia malayi and Trichinella spiralis: a comparison with Caenorhabditis elegans. Invertebrate Neuroscience, 7, pp. 219-226.

2006

Cook, A., Aptel, N., Portillo, V., Siney, E., Sihota, R., Holden-Dye, L. and Wolstenholme, A., 2006. Caenorhabditis elegans ivermectin receptors regulate locomotor behaviour and are functional orthologues of Haemonchus contortus receptors. Molecular and Biochemical Parasitology, 147 (1), pp. 118-125.

Alam, S., Laughton, D. L., Walding, A. and Wolstenholme, A. J., 2006. Human peripheral blood mononuclear cells express GABA(A) receptor subunits. Molecular Immunology, 43 (9), pp. 1432-1442.

Yusein, S., Velikova, N., Hardie, R., Wolstenholme, A. and Semenov, E., 2006. Interspecific variations in a histamine receptor gene, hclB, and primary characterization of the Drosophila melanogaster hclB mutants. Journal of Neurogenetics, 20 Jul-Dec (3-4), pp. 265-266.

Iovchev, M., Boutanaev, A., Ivanov, I., Wolstenholme, A., Nurminsky, D. and Semenov, E., 2006. Phylogenetic shadowing of a histamine-gated chloride channel involved in insect vision. Insect Biochemistry and Molecular Biology, 36 (1), pp. 10-17.

2005

Wolstenholme, A. J. and Rogers, A. T., 2005. Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics. Parasitology, 131, S85-S95.

Coles, G. C., Rhodes, A. C. and Wolstenholme, A., 2005. Rapid selection for ivermectin resistance in Haemonchus contortus. Veterinary Parasitology, 129 (3-4), pp. 345-347.

2004

Yates, D. M. and Wolstenholme, A. J., 2004. An ivermectin-sensitive glutamate-gated chloride channel subunit from Dirofilaria immitis. International Journal for Parasitology, 34 (9), pp. 1075-1081.

Coles, G. C., Jackson, F., Taylor, M. A. and Wolstenholme, A. J., 2004. Collaborating to tackle the problem of anthelmintic resistance. Veterinary Record, 155 (9), pp. 253-254.

Yates, D. M. and Wolstenholme, A. J., 2004. Dirofilaria immitis: identification of a novel ligand-gated ion channel-related polypeptide. Experimental Parasitology, 108 Nov-Dec (3-4), pp. 182-185.

Wolstenholme, A. J., Fairweather, I., Prichard, R., von Samson-Himmelstjerna, G. and Sangster, N. C., 2004. Drug resistance in veterinary helminths. Trends in Parasitology, 20 (10), pp. 469-476.

2003

Portillo, V., Jagannathan, S. and Wolstenholme, A. J., 2003. Distribution of glutamate-gated chloride channel subunits in the parasitic nematode Haemonchus contortus. The Journal of Comparative Neurology, 462 (2), pp. 213-222.

Valle, C., Troiani, A. R., Festucci, A., Pica-Mattoccia, L., Liberti, P., Wolstenholme, A., Francklow, K., Doenhoff, M. J. and Cioli, D., 2003. Sequence and level of endogenous expression of calcium channel beta subunits in Schistosoma mansoni displaying different susceptibilities to praziquantel. Molecular and Biochemical Parasitology, 130 (2), pp. 111-115.

Yates, D. M., Portillo, V. and Wolstenholme, A. J., 2003. The avermectin receptors of Haemonchus contortus and Caenorhabditis elegans. International Journal for Parasitology, 33 (11), pp. 1183-1193.

2002

Iovchev, M., Kodrov, P., Wolstenholme, A. J., Pak, W. L. and Semenov, E. P., 2002. Altered drug resistance and recovery from paralysis in Drosophila melanogaster with a deficient histamine-gated chloride channel. Journal of Neurogenetics, 16 Oct-Dec (4), pp. 249-261.

Georgiev, P. G., Wolstenholme, A. J., Pak, W. L. and Semenov, E. P., 2002. Differential responses to avermectins in ort mutants of Drosophila melanogaster. Pesticide Biochemistry and Physiology, 72 (2), pp. 65-71.

Martin, R. J., Robertson, A. P. and Wolstenholme, A. J., 2002. Mode of action of the macrocyclic lactones. In: Vercruysse, J. and Rew, R. S., eds. Macrocyclic lactones in antiparasitic therapy. Wallingford, UK: CABI publishing, pp. 125-140.

2001

Horoszok, L., Raymond, V., Sattelle, D. B. and Wolstenholme, A. J., 2001. GLC-3: a novel fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit from Caenorhabditis elegans. British Journal of Pharmacology, 132 (6), pp. 1247-1254.

Lind, R. J., Hardick, D. J., Blagbrough, I. S., Potter, B. V. L., Wolstenholme, A. J., Davies, A. R. L., Clough, M. S., Earley, F. G. P., Reynolds, S. E. and Wonnacott, S., 2001. [3H]-methyllycaconitine : a high affinity radioligand that labels invertebrate nicotinic acetylcholine receptors. Insect Biochemistry and Molecular Biology, 31 (6-7), pp. 533-542.

2000

Wolstenholme, A. J., Horoszok, L., Raymond, V. and Sattelle, D. B., 2000. GLC-3: A novel fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit from Caenorhabditis elegans. European Journal of Neuroscience, 12, p. 398.

Critten, C. L. and Wolstenholme, A. J., 2000. Ivermectin binds to recombinant nematode: Glutamate-gated chloride channels with high affinity. European Journal of Neuroscience, 12, p. 44.

Hejmadi, M. V., Jagannathan, S., Delany, N. S., Coles, G. C. and Wolstenholme, A. J., 2000. L-Glutamate binding sites of parasitic nematodes: an association with ivermectin resistance? Parasitology, 120, pp. 535-545.

1999

Whiteaker, P., Davies, A. R. L., Marks, M. J., Blagbrough, I. S., Potter, B. V. L., Wolstenholme, A. J., Collins, A. C. and Wonnacott, S., 1999. An autoradiographic study of the distribution of binding sites for the novel ∝7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain. European Journal of Neuroscience, 11 (8), pp. 2689-2696.

Davies, A. R. L., Hardick, D. J., Blagbrough, I. S., Potter, B. V. L., Wolstenholme, A. J. and Wonnacott, S., 1999. Characterisation of the binding of [3H]methyllycaconitine : a new radioligand for labelling α7-type neuronal nicotinic acetylcholine receptors. Neuropharmacology, 38 (5), pp. 679-690.